Bus Tickets from Santa Fe (Santa Fe), AR to Puerto Iguazú

Find affordable bus tickets from Santa Fe (Santa Fe), AR to Puerto Iguazú with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 25
from $88
TomorrowMay 26
TueMay 27
from $88
WedMay 28
ThuMay 29
FriMay 30
SatMay 31
SunJun 1

Cheap buses leaving Tuesday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 27 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: May 28 at
    Destination city: Puerto Iguazú
    Destination location: Terminal de Ómnibus
    Operated by: Expreso SingerExpreso Singer
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 27 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: May 28 at
    Destination city: Puerto Iguazú
    Destination location: Terminal de Ómnibus
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: May 27 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: May 27 at
    Destination city: Puerto Iguazú
    Destination location: Terminal de Ómnibus
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: May 27 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: May 27 at
    Destination city: Puerto Iguazú
    Destination location: Terminal de Ómnibus
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:
  • Departure time: May 27 at
    Departure city: Santa Fe
    Departure location: Estación Terminal de Ómnibius, Santa Fe
    Arrival time: May 28 at
    Destination city: Puerto Iguazú
    Destination location: Terminal de Ómnibus
    Operated by: Rio UruguayRio Uruguay
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Santa Fe to Puerto Iguazú: Trip Overview

Average ticket price$95
Average bus trip duration16h 15m
Number of daily buses5
Earliest bus departure12:15am
Distance558 miles (899 km)
Latest bus departure10:15pm

Santa Fe to Puerto Iguazú Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Fe to Puerto Iguazú.

Bus service from Santa Fe to Puerto Iguazú will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from Santa Fe to Puerto Iguazú, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Santa Fe (Santa Fe), AR - Puerto Iguazú

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/23
$61
05/24
$81
Today
$81
05/26
$81
05/27
$80
05/28
No data
05/29
No data
05/30
$66
busbud logoThe cheapest trip from Santa Fe to Puerto Iguazú was searched and found on May 23, 2025 with a price of $61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe to Puerto Iguazú, as early as possible.

You can expect to pay from $61 to $105 for a bus ticket from Santa Fe to Puerto Iguazú based on the last 2 days. You can expect to find the cheapest price for the trip at $66 which is on 2025-05-30.

Usually Emp.Asociadas - Río Uruguay will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Fe to Puerto Iguazú but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santa Fe to Puerto Iguazú, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Fe to Puerto Iguazú that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Santa Fe to Puerto Iguazú, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Santa Fe by bus?

Bus from Santa Fe to Puerto Iguazú

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Santa Fe

Buses Leaving from Santa Fe

Buses Going to Santa Fe

Popular Buses Connecting Puerto Iguazú

Buses Leaving from Puerto Iguazú

Buses Going to Puerto Iguazú