Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal San Luis | Estación Terminal de Ómnibius, Santa Fe | CheapestFastest |
Last refresh of the prices: Today at 3:04 PM -03.
Get from San Luis to Santa Fe
The journey takes about 10 hours 50 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Luis and Santa Fe?
Stops in San Luis
- A
Estación de Interconexión Regional de Ómnibus de San Luis
Avenida del Fundador, s/n, 5700 San Luis - BTerminal de San Luis, Av. del Fundador y Av. Santos Ortiz
Stops in Santa Fe
- A
Estación Terminal de Ómnibius, Santa Fe
Estación Terminal de Onmibus Belgrano 2900 , S3000GCH Santa Fe, Argentina
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Frequently asked questions about traveling from San Luis, AR to Santa Fe, AR by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Luis to Santa Fe?
The cheapest bus tickets from San Luis to Santa Fe start from $39. The average price for this route is around $47. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Luis to Santa Fe?
The average bus trip duration from San Luis to Santa Fe is 10h 50m, covering a distance of 345 miles (557 km). The quickest bus can get you there in 10h 40m and is operated by Flechabus.
Which bus companies service the San Luis to Santa Fe route?
Several major bus companies operate on this route with 2 buses available per day, including services from 20 de Junio, Andesmar, Flechabus, Tramat.
What is the earliest and latest departure time for the bus from San Luis to Santa Fe?
The earliest bus departs from San Luis to Santa Fe at 1:20am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from San Luis to Santa Fe?
A bus trip from San Luis to Santa Fe generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Luis to Santa Fe?
According to Busbud customers, the highest-rated bus company on this route is 20 de Junio, with an average rating of 4.0 out of 5 stars based on 588 reviews.
Which bus company has the best Wi-Fi from San Luis to Santa Fe?
Based on reviews on Busbud, the bus company 20 de Junio has the best Wi-Fi rating with a score of 2.3.
Which bus company has the most timely service from San Luis to Santa Fe?
According to Busbud traveller reviews, the most timely bus company on this route is 20 de Junio, with a punctuality rating of 4.1 out of 5 stars.
Which bus company has the cleanest buses from San Luis to Santa Fe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is 20 de Junio, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Luis, AR to Santa Fe, AR was searched and found on Dec 26, 2025 with a price of $50To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis, AR to Santa Fe, AR, as early as possible.
You can expect to pay from $50 to $62 for a bus ticket from San Luis, AR to Santa Fe, AR based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2025-12-29.
