Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rome Anagnina | Caltanissetta (Via Rochester) | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Caltanissetta (Via Rochester) | No tags | ||||
| Bus | Rome Fiumicino Airport | Caltanissetta (Via Rochester) | No tags | ||||
| Bus | Rome Anagnina | Caltanissetta (Via Rochester) | No tags | ||||
| Bus | Rome Tiburtina Bus Station | Caltanissetta (Via Rochester) | No tags |
Compare 2 ways to go from Rome to Caltanissetta
Among the sustainable travel choices, the Bus stands out as a good way to reach Caltanissetta. The journey takes about 15 hours 10 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$39 - $97 | Average Duration15h 10m | 12kg CO₂e | ||
Carpool | Average Price$66 - $66 | Average Duration10h | 21kg CO₂e |
Where are the popular stops in Rome and Caltanissetta?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Stops in Caltanissetta
- A
Corso Vittorio Emanuele II
Corso Vittorio Emanuele II, 97, 93100 Caltanissetta CL, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Rome to Caltanissetta by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Rome to Caltanissetta?
The cheapest bus tickets from Rome to Caltanissetta start from $39. The average price for this route is around $62. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Rome to Caltanissetta?
The average bus trip duration from Rome to Caltanissetta is 15h 10m, covering a distance of 308 miles (496 km). The quickest bus can get you there in 13h 15m and is operated by FlixBus.
Which bus companies service the Rome to Caltanissetta route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Rome to Caltanissetta?
The earliest bus departs from Rome to Caltanissetta at 4:40am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Rome to Caltanissetta?
A bus trip from Rome to Caltanissetta generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Caltanissetta was searched and found on Feb 5, 2026 with a price of $52To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Caltanissetta, as early as possible.
You can expect to pay from $52 to $58 for a bus ticket from Rome to Caltanissetta based on the last 2 days. You can expect to find the cheapest price for the trip at $52 which is on 2026-02-05.
What's the cheapest way to go from Rome to Caltanissetta?
The Bus is the cheapest travel choice for this destination
