Next departures

Next departures for Prague to Santander on August 25
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Prague (Na Knížecí)
Santander (Estacion de Autobuses)Cheapest
Flixbus
Prague (Central Bus Station Florenc)
Santander (Estacion de Autobuses)Fastest
Flixbus
Prague (Central Bus Station Florenc)
Santander (Estacion de Autobuses)No tags
Flixbus
Prague (Main Railway Station)
Santander (Estacion de Autobuses)No tags
Flixbus
Prague (Main Station - parking)
Santander (Estacion de Autobuses)No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Prague to Santander: Trip Overview

Average ticket price$177
Average bus trip duration1d 13h
Number of daily buses6
Earliest bus departure12:50pm
Distance972 miles (1567 km)
Latest bus departure11:05pm

Prague to Santander Bus

Busbud helps you find a bus from Prague to Santander. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Prague to Santander from the most reliable bus companies operating this trip.

Discover how much the bus trip from Prague to Santander will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Prague - Santander

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/21
No data
08/22
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Today
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08/24
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08/25
$147
08/26
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08/27
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08/28
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busbud logoThe cheapest trip from Prague to Santander was searched and found on Aug 25, 2025 with a price of $147

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Santander, as early as possible.

You can expect to pay from $147 to $177 for a bus ticket from Prague to Santander based on the last 2 days. You can expect to find the cheapest price for the trip at $147 which is on 2025-08-25.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Prague and Santander!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Prague to Santander, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Prague to Santander will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Prague to Santander.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Prague by bus?

Bus from Santander to Prague

Why choose Busbud?

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