Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Florenc | Lampugnano | CheapestFastest |
Last refresh of the prices: Yesterday at 11:53 PM CET.
Compare 2 ways to go from Prague to Milano
Among the sustainable travel choices, the carpool stands out as the good way to reach Milano. The journey takes about 11 hours 30 minutes and with fares starting at just $53, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$45 - $269 | Average Duration18h | 16kg CO₂e | ||
Carpool | Average Price$53 - $53 | Average Duration11h 30m | 27kg CO₂e |
Where are the popular stops in Prague and Milano?
Stops in Prague
- AAviatická, 161 08, Praha 6, Czechia
- B
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - CTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- DKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- EChlumecká, 198 00 Praha 20, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Milano
- BPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- CVia Giulio Natta, 228, 20151 Milano, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
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Frequently asked questions about traveling from Prague to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Prague to Milano?
The cheapest bus tickets from Prague to Milano start from $45. The average price for this route is around $87. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Prague to Milano?
The average bus trip duration from Prague to Milano is 18h, covering a distance of 402 miles (648 km). The quickest bus can get you there in 12h 35m and is operated by FlixBus.
Which bus companies service the Prague to Milano route?
Several major bus companies operate on this route with 78 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Prague to Milano?
The earliest bus departs from Prague to Milano at 2:30am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Prague to Milano?
A bus trip from Prague to Milano generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Prague to Milano?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1062 reviews.
Which bus company has the best Wi-Fi from Prague to Milano?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Prague to Milano?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Prague to Milano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Milano was searched and found on Dec 30, 2025 with a price of $75To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Milano, as early as possible.
You can expect to pay from $75 to $208 for a bus ticket from Prague to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $75 which is on 2025-12-30.
