Bus Tickets from Pittsburgh to St Louis

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TodayMay 29
from $79
TomorrowMay 30
SatMay 31
SunJun 1
MonJun 2
from $93
TueJun 3
WedJun 4
ThuJun 5

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 2 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: June 2 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 2 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: June 3 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 2 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: June 2 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 2 at
    Departure city: Pittsburgh
    Departure location: Pittsburgh Intermodal Station
    Arrival time: June 3 at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Pittsburgh to St Louis.

Bus
Average Price$75 - $169Average Duration13h 45m
22kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$157 - $259Average Duration23h 24m
82kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Pittsburgh to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 13 hours 45 minutes and with fares starting at just $75, it presents an excellent value for a comfortable ride.

2bus per day
13h 45mAverage Duration
$75Cheapest ticket
22kgCO₂ emissions

Bus Pittsburgh to St Louis: Trip Overview

Average ticket price$88
Average bus trip duration13h 45m
Number of daily buses2
Earliest bus departure1:35am
Distance557 miles (898 km)
Latest bus departure6:30pm

Pittsburgh to St Louis Bus

Busbud helps you find a bus from Pittsburgh to St Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Pittsburgh to St Louis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Pittsburgh to St Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Pittsburgh - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/27
$93
05/28
No data
Today
$71
05/30
No data
05/31
No data
06/01
No data
06/02
$85
06/03
No data
busbud logoThe cheapest trip from Pittsburgh to St Louis was searched and found on May 29, 2025 with a price of $71

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to St Louis, as early as possible.

You can expect to pay from $71 to $147 for a bus ticket from Pittsburgh to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $85 which is on 2025-06-02.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Pittsburgh and St Louis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Pittsburgh to St Louis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Pittsburgh to St Louis that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Pittsburgh to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Pittsburgh to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pittsburgh by bus?

Bus from Pittsburgh to St Louis

You can also go to St Louis by train

Train from Pittsburgh to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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