Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Odessa Central Bus Station | Florenc | CheapestFastest | ||||
 | Bus | Starosinnyi Square | Florenc | No tags | ||||
 | Bus | Odessa Avtobusna Zupynka | PRG Airport | No tags | ||||
| Bus | Starosinnyi Square | Florenc | No tags | ||||
| Bus | Odessa Avtobusna Zupynka | Prague (Central Bus Station Florenc) | No tags |
Last refresh of the prices: Yesterday at 4:00 PM EET.
Get from Odesa to Prague
The journey takes about 1 day, 15 hours 45 minutes and with fares starting at just $67, it presents an excellent value for a comfortable ride.
Where are the popular stops in Odesa and Prague?
Stops in Odesa
- AStarosinna St, 2, Odesa, Odessa Oblast, Ukraine
- BStarosinna St, 2, Odesa, Odessa Oblast, Ukraine
- CKolontaivs'ka Street, 69, Odesa, Odessa Oblast, Ukraine
- DNovoshchipnyi Ryad St 5, Odesa, Odessa Oblast, Ukraine 65000
- EPryvokzal'na Square, 2/1, Odesa, Odes'ka oblast, Ukraine, 65000
- FPryvokzal'na Square 2, Odesa, Odessa Oblast, Ukraine
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- CKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- DAviatická, 161 08, Praha 6, Czechia
- E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - F300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about traveling from Odesa to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Odesa to Prague?
The cheapest bus tickets from Odesa to Prague start from $67. The average price for this route is around $105. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Odesa to Prague?
The average bus trip duration from Odesa to Prague is 1d 15h, covering a distance of 785 miles (1267 km). The quickest bus can get you there in 9h 15m and is operated by Sindbad.
Which bus companies service the Odesa to Prague route?
Several major bus companies operate on this route with 17 buses available per day, including services from FlixBus, Ecolines, East West Eurolines, LIKEBUS, KLR Bus, Sindbad, Lux Bus, Musil Tour, East Express, Monobus, Infobus, Openline, DMD Group, LEX CLUB, Gal Transervice SRL.
What is the earliest and latest departure time for the bus from Odesa to Prague?
The earliest bus departs from Odesa to Prague at 5:10am. And the latest bus departs at 11:20pm.
What are the CO₂ emissions for the bus trip from Odesa to Prague?
A bus trip from Odesa to Prague generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Odesa to Prague?
According to Busbud customers, the highest-rated bus company on this route is KLR Bus, with an average rating of 4.2 out of 5 stars based on 19 reviews.
Which bus company has the best Wi-Fi from Odesa to Prague?
Based on reviews on Busbud, the bus company DMD Group has the best Wi-Fi rating with a score of 5.0.
Which bus company has the most timely service from Odesa to Prague?
According to Busbud traveller reviews, the most timely bus company on this route is Gal Transervice SRL, with a punctuality rating of 4.4 out of 5 stars.
Which bus company has the cleanest buses from Odesa to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is KLR Bus, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Odesa to Prague was searched and found on Dec 25, 2025 with a price of $82To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Odesa to Prague, as early as possible.
You can expect to pay from $82 to $202 for a bus ticket from Odesa to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $82 which is on 2025-12-25.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
