Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mexicali - Stop | Guaymas (El valiente) - Stop | CheapestFastest | ||||
 | Bus | Tufesa | Guaymas | No tags | ||||
 | Bus | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | Guaymas | No tags | ||||
| Bus | Mexicali - Stop | Guaymas (El valiente) - Stop | No tags | ||||
| Bus | Tufesa | Guaymas | No tags |
Last refresh of the prices: Today at 12:44 PM PDT.
Get from Mexicali to Guaymas
The journey takes about 11 hours 10 minutes and with fares starting at just $63, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mexicali and Guaymas?
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
Stops in Guaymas
- A
Terminal TAP de Guaymas
Calzada Agustín García López #915, Colonia Delicias, 85440 Guaymas
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Frequently asked questions about traveling from Mexicali to Guaymas by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mexicali to Guaymas?
The cheapest bus tickets from Mexicali to Guaymas start from $63. The average price for this route is around $97. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mexicali to Guaymas?
The average bus trip duration from Mexicali to Guaymas is 11h 10m, covering a distance of 421 miles (678 km). The quickest bus can get you there in 9h and is operated by Interbus de Sinaloa.
Which bus companies service the Mexicali to Guaymas route?
Several major bus companies operate on this route with 16 buses available per day, including services from Tufesa, Elite, Interbus de Sinaloa, Aguacaliente, Aguacaliente.
What is the earliest and latest departure time for the bus from Mexicali to Guaymas?
The earliest bus departs from Mexicali to Guaymas at 12:00am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Mexicali to Guaymas?
A bus trip from Mexicali to Guaymas generates an estimated 16.938924999999998 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mexicali to Guaymas?
According to Busbud customers, the highest-rated bus company on this route is Interbus de Sinaloa, with an average rating of 4.0 out of 5 stars based on 4 reviews.
Which bus company has the best Wi-Fi from Mexicali to Guaymas?
Based on reviews on Busbud, the bus company Tufesa has the best Wi-Fi rating with a score of 3.0.
Which bus company has the most timely service from Mexicali to Guaymas?
According to Busbud traveler reviews, the most timely bus company on this route is Interbus de Sinaloa, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from Mexicali to Guaymas?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Aguacaliente, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexicali to Guaymas was searched and found on Mar 30, 2026 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Guaymas, as early as possible.
You can expect to pay from $68 to $97 for a bus ticket from Mexicali to Guaymas based on the last 2 days. You can expect to find the cheapest price for the trip at $70 which is on 2026-04-06.
