Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mainz | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Cheapest | ||||
| Bus | Mainz | Madrid (South) | Fastest | ||||
| Bus | Mainz | Madrid (South) | No tags | ||||
| Bus | Mainz | Madrid (South) | No tags | ||||
| Bus | Mainz | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | No tags |
Last refresh of the prices: Yesterday at 12:51 PM CET.
Get from Mainz to Madrid
The journey takes about 1 day, 7 hours 40 minutes and with fares starting at just $145, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mainz and Madrid?
Stops in Mainz
- A
Mainz
Hechtsheimer Str. 65, 55131 Mainz, Germany - B
Mainz- Kaiser-Wilhelm-Ring 16- gegenüberliegende Straßenseite
Kaiser-Wilhelm-Ring 16 (gegenüberliegende Straßenseite), 55118 Mainz - Cflibco.com bus stop, Kaiser-Wilhelm-Ring, 55118 Mainz, Germany
Stops in Madrid
- BMendez Alvaro, 83, , Madrid, 28045, Spain
- CAvenida de América, 9, 28002 Madrid, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - FMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Mainz to Madrid by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mainz to Madrid?
The cheapest bus tickets from Mainz to Madrid start from $145. The average price for this route is around $183. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mainz to Madrid?
The average bus trip duration from Mainz to Madrid is 1d 7h, covering a distance of 871 miles (1404 km). The quickest bus can get you there in 1d 4h and is operated by FlixBus.
Which bus companies service the Mainz to Madrid route?
Several major train operators operate on this route with 7 trains available per day.
What is the earliest and latest departure time for the bus from Mainz to Madrid?
The earliest bus departs from Mainz to Madrid at 1:00am. And the latest bus departs at 10:40pm.
What are the CO₂ emissions for the bus trip from Mainz to Madrid?
A bus trip from Mainz to Madrid generates an estimated 35 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mainz to Madrid was searched and found on Jan 11, 2026 with a price of $123To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mainz to Madrid, as early as possible.
