Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Estación Sur | Brussels North Train Station | Cheapest | ||||
| Bus | Aeropuerto Madrid - Barajas T4 (E) | Brussels-South (Gare du Midi) | Fastest | ||||
BlaBlaCar Bus - Alsa + BlaBlaCar Bus | Bus | Estación Sur | Brussels-South (Gare du Midi) | No tags | ||||
 | Bus | Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4 | Brussels North Train Station | No tags | ||||
| Bus | Estación Sur | Brussels-South (Gare du Midi) | No tags |
Last refresh of the prices: Yesterday at 2:38 PM CET.
Compare 2 ways to go from Madrid to Brussels
Among the sustainable travel choices, the carpool stands out as the good way to reach Brussels. The journey takes about 15 hours 40 minutes and with fares starting at just $73, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$50 - $281 | Average Duration23h 10m | 33kg CO₂e | ||
Carpool | Average Price$73 - $153 | Average Duration15h 40m | 55kg CO₂e |
Where are the popular stops in Madrid and Brussels?
Stops in Madrid
- AMendez Alvaro, 83, , Madrid, 28045, Spain
- CAvenida de América, 9, 28002 Madrid, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - FMadrid Atocha railway station, Plaza del Emperador Carlos V, 28045 Madrid, Spain
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Frequently asked questions about traveling from Madrid to Brussels by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Madrid to Brussels?
The cheapest bus tickets from Madrid to Brussels start from $50. The average price for this route is around $93. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Madrid to Brussels?
The average bus trip duration from Madrid to Brussels is 23h 10m, covering a distance of 823 miles (1328 km). The quickest bus can get you there in 20h 5m and is operated by BlaBlaCar Bus.
Which bus companies service the Madrid to Brussels route?
Several major bus companies operate on this route with 18 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Madrid to Brussels?
The earliest bus departs from Madrid to Brussels at 9:25am. And the latest bus departs at 11:55pm.
What are the CO₂ emissions for the bus trip from Madrid to Brussels?
A bus trip from Madrid to Brussels generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Madrid to Brussels?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11239 reviews.
Which bus company has the best Wi-Fi from Madrid to Brussels?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Madrid to Brussels?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Madrid to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madrid to Brussels was searched and found on Dec 24, 2025 with a price of $69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madrid to Brussels, as early as possible.
You can expect to pay from $69 to $278 for a bus ticket from Madrid to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2025-12-31.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
