Bus Tickets from Harrisburg to Florence, SC, US

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TodayJun 28
TomorrowJun 29
from $119
MonJun 30
TueJul 1
WedJul 2
ThuJul 3
FriJul 4
SatJul 5

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: June 29 at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: June 30 at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: June 29 at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: June 30 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: June 30 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Harrisburg
    Departure location: Harrisburg Bus Station
    Arrival time: July 1 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: June 29 at
    Departure city: Harrisburg
    Departure location: Harrisburg
    Arrival time: June 30 at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Harrisburg to Florence.

Average Price$119 - $203Average Duration21h 40m
18kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average Price$246 - $258Average Duration14h 5m
66kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Harrisburg to Florence

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 21 hours 40 minutes and with fares starting at just $119, it presents an excellent value for a comfortable ride.

4bus per day
21h 40mAverage Duration
$119Cheapest ticket
18kgCO₂ emissions

Bus Harrisburg to Florence: Trip Overview

Average ticket price$137
Average bus trip duration21h 40m
Number of daily buses4
Earliest bus departure12:30pm
Distance448 miles (721 km)
Latest bus departure11:20pm

Harrisburg to Florence Bus

With Busbud, comparing and booking tickets for a bus from Harrisburg to Florence is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Harrisburg to Florence will be provided by the most trusted bus companies.

Discover how much the bus trip from Harrisburg to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Harrisburg - Florence, SC, US

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Harrisburg to Florence.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Harrisburg to Florence, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Harrisburg to Florence will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Harrisburg to Florence, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Harrisburg to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Harrisburg to Florence

You can also go to Florence by train

Train from Harrisburg to Florence

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