Bus Tickets from Frankfurt am Main to Brno

Next departures

Next departures for Frankfurt am Main to Brno on September 8
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
RegioJet + RegioJet
Frankfurt - Main bus station
Hlavní nádražíCheapestFastest

Accepted payments

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Compare 3 ways to go from Frankfurt am Main to Brno.

Bus
Average Price$49 - $173Average Duration13h 15m
15kg CO₂e5 out of 5 stars
Train
Average Price$38 - $328Average Duration9h 6m
14kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average Price$67 - $74Average Duration7h
24kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Frankfurt am Main to Brno

Among the sustainable travel choices, the carpool stands out as the good way to reach Brno. The journey takes about 7 hours and with fares starting at just $67, it presents an excellent value for a comfortable ride.

1carpool per day
7hAverage Duration
$67Cheapest ticket
24kgCO₂ emissions

Bus Frankfurt am Main to Brno: Trip Overview

Average ticket price$72
Average bus trip duration13h 15m
Number of daily buses13
Earliest bus departure1:15am
Distance361 miles (581 km)
Latest bus departure11:59pm

Frankfurt am Main to Brno Bus

Busbud helps you find a bus from Frankfurt am Main to Brno. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Frankfurt am Main to Brno will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Brno from Frankfurt am Main, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Frankfurt am Main - Brno

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/02
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Today
$46
09/05
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09/06
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09/08
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09/09
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busbud logoThe cheapest trip from Frankfurt am Main to Brno was searched and found on Sep 4, 2025 with a price of $46

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frankfurt am Main to Brno, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Frankfurt am Main and Brno!

Much more than a mere vehicle taking you from Frankfurt am Main to Brno, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Frankfurt am Main to Brno.

Tune out to the fine sounds of your best music playlist on your bus trip from Frankfurt am Main to Brno while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Frankfurt am Main to Brno?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Frankfurt am Main by bus?

Bus from Brno to Frankfurt am Main

You can also go to Brno by train

Train from Frankfurt am Main to Brno

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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