Next departures for Boston to Indianapolis on December 25
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Boston (South Station)
Indianapolis Bus Station
Cheapest
Bus
Boston (South Station)
Indianapolis Bus Station
Fastest
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Bus
Boston (South Station)
Downtown Transit Center
No tags
Next departures for Boston to Indianapolis on December 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Brookline
Downtown Transit Center
Cheapest
Bus
Boston (South Station)
Indianapolis Bus Station
Fastest
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Bus
Boston (South Station)
Downtown Transit Center
No tags
Next departures for Boston to Indianapolis on December 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
Downtown Transit Center
Cheapest
Bus
Boston (South Station)
Indianapolis Bus Station
Fastest
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Bus
Brookline
Downtown Transit Center
No tags
Next departures for Boston to Indianapolis on December 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
Indianapolis Bus Station
Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
Downtown Transit Center
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Bus
Boston (South Station)
Indianapolis Bus Station
No tags
Bus
Brookline
Downtown Transit Center
No tags
Last refresh of the prices: Today at 7:54 AM EST.
Compare 2 ways to go from Boston to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 1 day, 5 hours 10 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Boston, MA, US to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Boston to Indianapolis?
The cheapest bus tickets from Boston to Indianapolis start from $105. The average price for this route is around $193. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Boston to Indianapolis?
The average bus trip duration from Boston to Indianapolis is 1d 5h, covering a distance of 805 miles (1297 km). The quickest bus can get you there in 23h 5m and is operated by Greyhound.
Which bus companies service the Boston to Indianapolis route?
Several major bus companies operate on this route with 16 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Boston to Indianapolis?
The earliest bus departs from Boston to Indianapolis at 1:30am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Boston to Indianapolis?
A bus trip from Boston to Indianapolis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Boston to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Boston to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Boston to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Boston to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/22
$351
12/23
$292
Today
$203
12/25
$198
12/26
$224
12/27
$208
12/28
$164
12/29
$211
The cheapest trip from Boston, MA, US to Indianapolis was searched and found on Dec 28, 2025 with a price of $164
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Indianapolis, as early as possible.
You can expect to pay from $164 to $351 for a bus ticket from Boston, MA, US to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $164 which is on 2025-12-28.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Boston, MA, US to Indianapolis?
The bus is the cheapest travel choice for this destination