Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Thessaloniki 28 Monastiriou Street | Brussels Airport | Cheapest | ||||
| Bus | Thessaloniki 28 Monastiriou Street | Brussels North Train Station | Fastest | ||||
| Bus | Thessaloniki 28 Monastiriou Street | Brussels South (Gare du Midi) | No tags |
Last refresh of the prices: Last Monday at 11:33 AM EET.
Get from Thessaloniki to Brussels
The journey takes about 2 days, 2 hours 10 minutes, and with fares starting at just R 2 301, it presents an excellent value for a comfortable ride.
Where are the popular stops in Thessaloniki and Brussels?
Stops in Thessaloniki
- ALeof. Dendropotamou, Ampelokipi Menemeni 546 28, Greece
- BMonastiriou 63, Thessaloniki 546 27, Greece
- C
Selanik Makedonya KTEL Otogarı
Selanik KTEL Bus Station, Giannitson 244, Thessaloniki 546 28, Greece - D
Taskou Papageorgiou
Taskou Papageorgiou 5, Thessaloniki 546 31, Greece - E
Michail Kalou 16
Michail Kalou 16, Thessaloniki 546 29, Greece - F
Makedonya Şehirlerarası Otogarı
Monastiriou 63, Thessaloniki 546 27, Greece
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Compare bus companies
Based on 11962 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 2 301
Frequently asked questions about travelling from Thessaloniki to Brussels by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Thessaloniki to Brussels?
The cheapest bus tickets from Thessaloniki to Brussels start at R 2 301. The average price for this route is around R 2 998. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Thessaloniki to Brussels?
The average bus journey time from Thessaloniki to Brussels is 2d 2h, covering a distance of 1821 km. The fastest bus gets you there in 1d 23h and is operated by FlixBus.
Which bus companies service the Thessaloniki to Brussels route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Thessaloniki to Brussels?
The earliest bus departs from Thessaloniki to Brussels at 17:30. And the latest bus departs at 17:30.
What are the CO₂ emissions for the bus trip from Thessaloniki to Brussels?
A bus trip from Thessaloniki to Brussels produces an estimated 46 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Thessaloniki to Brussels was searched and found on 09 Jan 2026 with a price of R 2 681To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Thessaloniki to Brussels as early as possible.
You can expect to pay from R 2 681 to R 2 995 for a bus ticket from Thessaloniki to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 681, which is on 2026-01-09.
