Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Buses Andimar + FlixBus | Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags | ||||
FlixBus + Buses Andimar | Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags | ||||
 | Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags | ||||
| Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags | ||||
| Bus | Talca (Cruce Varoli) | La Serena (Bus terminal La Serena) | No tags |
Get from Talca to La Serena
The journey takes about 11 hours, and with fares starting at just R 360, it presents an excellent value for a comfortable ride.
Where are the popular stops in Talca and La Serena?
Stops in Talca
- ADos Sur / Doce y Trece Oriente, Talca, VII Región, Chile
- B
Parada de Autobus Talca Varoli
Rho 1131, Talca, VII Región, Chile - C
Parada de Autobus Talca Cruce Varoli
Veintiuno Ote 253, Talca, VII Región, Chile - D
Estación de Ferrocarriles de Talca
Once Ote 900-1002, Talca, VII Región, Chile - E
Terminal Tur Bus de Talca
Trece Ote 851-889, Talca, VII Región, Chile - F
Cruce Sur San Javier
Sgto Aldea 2456, San Javier, VII Región, Chile
Stops in La Serena
- AAmunátegui 107, La Serena, Región de Coquimbo, Chile
- B
Rotonda La Serena
Panamericana Norte 208, La Serena, Región de Coquimbo, Chile
Compare bus companies
Based on 12162 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. FlixBus ticket prices on this trip start at R 360
Frequently asked questions about travelling from Talca to La Serena, CL by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Talca to La Serena?
The cheapest bus tickets from Talca to La Serena start at R 360. The average price for this route is around R 530. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Talca to La Serena?
The average bus journey time from Talca to La Serena is 11h, covering a distance of 617 km. The fastest bus gets you there in 10h 35m and is operated by FlixBus.
Which bus companies service the Talca to La Serena route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Talca to La Serena?
The earliest bus departs from Talca to La Serena at 06:45. And the latest bus departs at 17:45.
What are the CO₂ emissions for the bus trip from Talca to La Serena?
A bus trip from Talca to La Serena produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Talca to La Serena, CL was searched and found on 31 Jan 2026 with a price of R 389To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Talca to La Serena, CL as early as possible.
You can expect to pay from R 389 to R 630 for a bus ticket from Talca to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at R 389, which is on 2026-01-31.
