How much is the bus ticket from St. Louis to Chicago?

The cheapest bus tickets from St. Louis to Chicago start at R 545. The average price for this route is around R 812. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from St. Louis to Chicago?

The average bus journey time from St. Louis to Chicago is 6h 25m, covering a distance of 423 km. The fastest bus gets you there in 5h 50m and is operated by FlixBus .

Which bus companies service the St. Louis to Chicago route?

Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus , Greyhound , Burlington Trailways , Amtrak .

What is the earliest and latest departure time for the bus from St. Louis to Chicago?

The earliest bus departs from St. Louis to Chicago at 02:00. And the latest bus departs at 23:30.

What are the CO₂ emissions for the bus trip from St. Louis to Chicago?

A bus trip from St. Louis to Chicago produces an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from St. Louis to Chicago?

According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways , with an average rating of 4.2 out of 5 stars based on 20 reviews.

Which bus company has the best Wi-Fi from St. Louis to Chicago?

Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

Which bus company offers the most punctual service from St. Louis to Chicago?

According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways , with a punctuality rating of 5.0 out of 5 stars.

Which bus company has the cleanest buses from St. Louis to Chicago?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways , with a cleanliness rating of 5.0 out of 5 stars.

Bus St. Louis to Chicago from R 568 | Refundable Tickets

Next departures

Next departures from St. Louis to Chicago on 15 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	CheapestFastest
	23:00	Gateway Station	10h 15m	09:15	Chicago (Union Station), IL	No tags
FlixBus + Greyhound Lines, Inc.	16:00	Gateway Station	7h 35m	23:35	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 16 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	CheapestFastest
	08:45	Gateway Station	11h 25m	20:10	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	16:00	Gateway Station	7h 35m	23:35	Chicago 95Th & Dan Ryan	No tags
	02:00	Gateway Station	11h 40m	13:40	Chicago 95Th & Dan Ryan	No tags
	13:55	Gateway Station	9h 5m	23:00	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 17 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	CheapestFastest
	23:00	Gateway Station	10h 15m	09:15	Chicago (Union Station), IL	No tags
	08:45	Gateway Station	11h 25m	20:10	Downtown Greyhound Station	No tags
FlixBus + Greyhound Lines, Inc.	16:00	Gateway Station	7h 35m	23:35	Chicago 95Th & Dan Ryan	No tags
	02:00	Gateway Station	11h 40m	13:40	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 18 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
09:30	Gateway Station	7h	16:30	Downtown Greyhound Station	Cheapest
23:30	Gateway Station	5h 50m	05:20	Chicago 95Th & Dan Ryan	Fastest
23:00	Gateway Station	10h 15m	09:15	Chicago (Union Station), IL	No tags
16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	No tags
13:55	Gateway Station	9h 5m	23:00	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 19 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	Cheapest
23:30	Gateway Station	5h 50m	05:20	Chicago 95Th & Dan Ryan	Fastest
23:00	Gateway Station	10h 15m	09:15	Chicago (Union Station), IL	No tags
09:30	Gateway Station	7h	16:30	Downtown Greyhound Station	No tags
13:55	Gateway Station	9h 5m	23:00	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 20 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	Cheapest
23:30	Gateway Station	5h 50m	05:20	Chicago 95Th & Dan Ryan	Fastest
23:00	Gateway Station	10h 15m	09:15	Chicago (Union Station), IL	No tags
09:30	Gateway Station	7h	16:30	Downtown Greyhound Station	No tags
13:55	Gateway Station	9h 5m	23:00	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 21 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
09:30	Gateway Station	7h	16:30	Downtown Greyhound Station	Cheapest
23:30	Gateway Station	5h 50m	05:20	Chicago 95Th & Dan Ryan	Fastest
23:00	Gateway Station	10h 15m	09:15	Chicago (Union Station), IL	No tags
16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	No tags
13:55	Gateway Station	9h 5m	23:00	Chicago 95Th & Dan Ryan	No tags

Next departures from St. Louis to Chicago on 22 December
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	09:30	Gateway Station	7h	16:30	Downtown Greyhound Station	Cheapest
	23:30	Gateway Station	5h 50m	05:20	Chicago 95Th & Dan Ryan	Fastest
	16:00	Gateway Station	6h 5m	22:05	Downtown Greyhound Station	No tags
	13:55	Gateway Station	9h 5m	23:00	Chicago 95Th & Dan Ryan	No tags
FlixBus + Greyhound Lines, Inc.	16:00	Gateway Station	7h 35m	23:35	Chicago 95Th & Dan Ryan	No tags

Last refresh of the prices: Today at 8:31 AM CST.

Compare 2 ways to travel from St. Louis to Chicago

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Chicago. The journey takes about 5 hours 5 minutes and with fares starting at just R 502, it presents an excellent value for a comfortable ride.

5train per day

5h 5mAverage duration

423 kmDistance

38kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 545 - R 3 211	Average duration6h 25m	CO₂ emissions 11kg CO₂e
Train	Average priceR 502 - R 1 677	Average duration5h 5m	CO₂ emissions 38kg CO₂e

Where are the popular stops in St. Louis and Chicago?

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Stops in Chicago

A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA
Visit page
B
Chicago O'Hare International Airport
C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA
D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA
E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA
F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA

Compare bus companies

FlixBus

3.5/511 621 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

Greyhound

3.5/587 433 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

According to 27 reviews, Greyhound received a 3.1-star rating for this journey. Travellers were especially satisfied with the temperature and the departure location, but some complained about the value for money. Greyhound ticket prices on this trip start at R 657

Greyhound St. Louis Chicago recent customer reviews

My trip was changed then cancelled and the next bus took 2 hrs . My connection to complete my trip made me arrive at my final destination at 4 am to an empty station where I couldn't get any assistance. Couldn't get a taxi at that hour there. It was a very horrible experience.

Raydell W.

3 July 2023

My first time from along time to many stops little confusing if we were close or what time we really will be in Chicago in all Ok!

Shelia S.

18 July 2019

Very professional and courteous. Actually, quite a bit more professional and less stressful than air travel presently. Pleasantly surprised!

Laura M.

18 October 2018

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

WiFi5

Amtrak

4/55 648 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

WiFi3.6

Users have praised the service for being on time, comfortable, and convenient with friendly conductors. However, there were concerns about inconsistent behavior from staff towards passengers of different races during ticket checks and upon arrival.

Amtrak St. Louis Chicago recent customer reviews

Smooth ride. The man who did our tickets from St. Louis we noticed after checking white people's tickets he said thanks and have a great day. To black people he said nothing. Then upon arriving in Chicago that man offered no one a hand down or said goodbye.

Yvonne H.

27 September 2024

Fabulous! Train is the way to go for this distance!! On time, comfortable, friendly conductors, and SO convenient!

Kendra H.

3 April 2024

Good but train was cancelled and coming with bus. I pay too much money

Anshul P.

23 December 2024

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from St. Louis to Chicago by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from St. Louis to Chicago?
The cheapest bus tickets from St. Louis to Chicago start at R 545. The average price for this route is around R 812. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from St. Louis to Chicago?
The average bus journey time from St. Louis to Chicago is 6h 25m, covering a distance of 423 km. The fastest bus gets you there in 5h 50m and is operated by FlixBus.
Which bus companies service the St. Louis to Chicago route?
Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Greyhound, Burlington Trailways, Amtrak.
What is the earliest and latest departure time for the bus from St. Louis to Chicago?
The earliest bus departs from St. Louis to Chicago at 02:00. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from St. Louis to Chicago?
A bus trip from St. Louis to Chicago produces an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from St. Louis to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which bus company has the best Wi-Fi from St. Louis to Chicago?
Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company offers the most punctual service from St. Louis to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

13/12

R 1 050

14/12

R 1 136

Today

R 981

16/12

R 964

17/12

R 843

18/12

R 774

19/12

R 1 015

20/12

R 843

The cheapest trip from St. Louis to Chicago was searched and found on 18 Dec 2025 with a price of R 774

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Chicago as early as possible.

You can expect to pay from R 774 to R 7 087 for a bus ticket from St. Louis to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 774, which is on 2025-12-18.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.