Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Calle Navas de Tolosa, 2 | Perrache | CheapestFastest |
Last refresh of the prices: Last Saturday at 8:39 AM CET.
Get from Santander to Lyon
The journey takes about 19 hours 5 minutes, and with fares starting at just R 1 736, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santander and Lyon?
Stops in Santander
- ACalle Navas de Tolosa, 2, 39002 Santander, Cantabria, Spain
- C
Av. de los Castros 43A
Av. de los Castros 43A, 39005 Santander, Cantabria, Spain - D
Calle Camarreal-Ojaiz
Calle Camarreal-Ojaiz, 52, 39011 Santander, Cantabria, Spain - E
Av. de Pontejos
Av. de Pontejos, 33A, 39005 Santander, Cantabria, Spain - F
Estación Marítima
39002 Santander, Cantabria, Spain
Stops in Lyon
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
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Frequently asked questions about travelling from Santander to Lyon by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santander to Lyon?
The cheapest bus tickets from Santander to Lyon start at R 1 736. The average price for this route is around R 2 656. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santander to Lyon?
The average bus journey time from Santander to Lyon is 19h 5m, covering a distance of 730 km. The fastest bus gets you there in 15h 40m and is operated by FlixBus.
Which bus companies service the Santander to Lyon route?
What is the earliest and latest departure time for the bus from Santander to Lyon?
The earliest bus departs from Santander to Lyon at 09:00. And the latest bus departs at 20:45.
What are the CO₂ emissions for the bus trip from Santander to Lyon?
A bus trip from Santander to Lyon produces an estimated 18.228675000000003 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Santander to Lyon?
According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 61531 reviews.
Which bus company has the best Wi-Fi from Santander to Lyon?
Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.
Which bus company offers the most punctual service from Santander to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Santander to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santander to Lyon was searched and found on 07 Apr 2026 with a price of R 885To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Lyon as early as possible.
You can expect to pay from R 885 to R 2 546 for a bus ticket from Santander to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 885, which is on 2026-04-07.
