Bus from Santa Fe, AR to Santiago del Estero: Tickets & Timetables

Previously seen journeys

Next departures from Santa Fe to Santiago del Estero on 15 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
El PracticoBus
Estación Terminal de Ómnibius, Santa Fe
Terminal de Ómnibus de Santiago del EsteroNo tags
FlechabusBus
Estación Terminal de Ómnibius, Santa Fe
Terminal de Ómnibus de Santiago del EsteroNo tags
FlechabusBus
Estación Terminal de Ómnibius, Santa Fe
Terminal de Ómnibus de Santiago del EsteroNo tags
El PracticoBus
Estación Terminal de Ómnibius, Santa Fe
Terminal de Ómnibus de Santiago del EsteroNo tags
FlechabusBus
Estación Terminal de Ómnibius, Santa Fe
Terminal de Ómnibus de Santiago del EsteroNo tags

Get from Santa Fe to Santiago del Estero

This route is served by bus only

The journey takes about 9 hours 20 minutes, and with fares starting at just R 522, it presents an excellent value for a comfortable ride.

1bus per day
9h 20mAverage duration
551 kmDistance
14kgCO₂ emissions

Frequently asked questions about travelling from Santa Fe, AR to Santiago del Estero by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Santa Fe to Santiago del Estero?

    The cheapest bus tickets from Santa Fe to Santiago del Estero start at R 522. The average price for this route is around R 743. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Santa Fe to Santiago del Estero?

    The average bus journey time from Santa Fe to Santiago del Estero is 9h 20m, covering a distance of 551 km. The fastest bus gets you there in 9h and is operated by Flechabus.

  3. Which bus companies service the Santa Fe to Santiago del Estero route?

    Several major bus companies operate on this route with 1 buses available per day, including services from Flechabus, El Practico.

  4. What is the earliest and latest departure time for the bus from Santa Fe to Santiago del Estero?

    The earliest bus departs from Santa Fe to Santiago del Estero at 19:40. And the latest bus departs at 20:10.

  5. What are the CO₂ emissions for the bus trip from Santa Fe to Santiago del Estero?

    A bus trip from Santa Fe to Santiago del Estero produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Santa Fe to Santiago del Estero?

    According to Busbud customers, the highest-rated bus company on this route is El Practico, with an average rating of 4.5 out of 5 stars based on 556 reviews.

  7. Which bus company has the best Wi-Fi from Santa Fe to Santiago del Estero?

    Based on reviews on Busbud, the bus company El Practico has the best Wi-Fi rating with a score of 2.4.

  8. Which bus company offers the most punctual service from Santa Fe to Santiago del Estero?

    According to Busbud traveller reviews, the most punctual bus company on this route is El Practico, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Santa Fe to Santiago del Estero?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is El Practico, with a cleanliness rating of 4.7 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/12
R 566
14/12
No data
Today
No data
16/12
R 427
17/12
No data
18/12
R 453
19/12
No data
20/12
No data
busbud logoThe cheapest trip from Santa Fe, AR to Santiago del Estero was searched and found on 16 Dec 2025 with a price of R 427

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Fe, AR to Santiago del Estero as early as possible.

You can expect to pay from R 427 to R 979 for a bus ticket from Santa Fe, AR to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at R 427, which is on 2025-12-16.

Usually El Practico will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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