Bus from Milano to Lyon: Tickets & Timetables

Next bus departures

Next departures from Milano to Lyon on 16 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus Bus
Lampugnano bus station
PerracheCheapest
Flixbus Bus
Lampugnano bus station
PerracheFastest
Flixbus Bus
Lampugnano bus station
PerracheNo tags
ItabusBus
Lampugnano
Lyon Lyon Perrache Bus StationNo tags
Flixbus Bus
Lampugnano bus station
PerracheNo tags

Last refresh of the prices: Today at 5:19 AM CET.

Compare 3 ways to travel from Milano to Lyon

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 4 hours 50 minutes and with fares starting at just R 565, it presents an excellent value for a comfortable ride.

1carpool per day
4h 50mAverage duration
340 kmDistance
14kgCO₂ emissions
Average priceR 332 - R 2 990Average duration8h
8kg CO₂e
Average priceR 781 - R 4 000Average duration4h 39m
8kg CO₂e
Carpool
Average priceR 565 - R 941Average duration4h 50m
14kg CO₂e

Frequently asked questions about travelling from Milano to Lyon by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Milano to Lyon?

    The cheapest bus tickets from Milano to Lyon start at R 332. The average price for this route is around R 761. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Milano to Lyon?

    The average bus journey time from Milano to Lyon is 8h, covering a distance of 336 km. The fastest bus gets you there in 5h 30m and is operated by BlaBlaCar Bus.

  3. Which bus companies service the Milano to Lyon route?

    Several major bus companies operate on this route with 21 buses available per day, including services from FlixBus, BlaBlaCar Bus, Itabus, Union Ivkoni.

  4. What is the earliest and latest departure time for the bus from Milano to Lyon?

    The earliest bus departs from Milano to Lyon at 00:30. And the latest bus departs at 23:55.

  5. What are the CO₂ emissions for the bus trip from Milano to Lyon?

    A bus trip from Milano to Lyon produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Milano to Lyon?

    According to Busbud customers, the highest-rated bus company on this route is Itabus, with an average rating of 3.8 out of 5 stars based on 951 reviews.

  7. Which bus company has the best Wi-Fi from Milano to Lyon?

    Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 3.0.

  8. Which bus company offers the most punctual service from Milano to Lyon?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Milano to Lyon?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Itabus, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/12
R 333
14/12
R 333
Today
R 385
16/12
R 385
17/12
R 375
18/12
R 416
19/12
R 458
20/12
R 416
busbud logoThe cheapest trip from Milano to Lyon was searched and found on 13 Dec 2025 with a price of R 333

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Lyon as early as possible.

You can expect to pay from R 333 to R 2 309 for a bus ticket from Milano to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 375, which is on 2025-12-17.

Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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