Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | WJW Investments Bus Stop | Knoxville Bus Station | CheapestFastest |
Last refresh of the prices: Last Wednesday at 9:38 PM EST.
Get from Lexington to Knoxville
The journey takes about 3 hours 45 minutes, and with fares starting at just R 600, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lexington and Knoxville?
Stops in Lexington
- A477 W New Circle Rd, Lexington, KY 40511
- B1801 Alexandria Dr, Lexington, KY 40504, USA
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87508 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 600
Frequently asked questions about travelling from Lexington, KY to Knoxville, TN by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Lexington to Knoxville?
The cheapest bus tickets from Lexington to Knoxville start at R 600. The average price for this route is around R 945. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Lexington to Knoxville?
The average bus journey time from Lexington to Knoxville is 3h 45m, covering a distance of 237 km. The fastest bus gets you there in 3h 45m and is operated by Greyhound.
Which bus companies service the Lexington to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Lexington to Knoxville?
The earliest bus departs from Lexington to Knoxville at 15:10. And the latest bus departs at 15:45.
What are the CO₂ emissions for the bus trip from Lexington to Knoxville?
A bus trip from Lexington to Knoxville produces an estimated 6 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lexington, KY to Knoxville, TN was searched and found on 22 Jan 2026 with a price of R 480To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lexington, KY to Knoxville, TN as early as possible.
You can expect to pay from R 480 to R 690 for a bus ticket from Lexington, KY to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at R 480, which is on 2026-01-22.
