Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | La Crosse (U of WI) | Minneapolis (Mall of America) | Cheapest | ||||
| Bus | 314 Jay St., La Crosse | Minneapolis (Mall of America) | Fastest | ||||
Jefferson Lines + Jefferson Lines | Bus | La Crosse (U of WI) | Minneapolis (Mall of America) | No tags | ||||
| Bus | 314 Jay St., La Crosse | Minneapolis | No tags | ||||
| Bus | 314 Jay St., La Crosse | Minneapolis | No tags |
Last refresh of the prices: Today at 1:27 AM CST.
Get from La Crosse to Minneapolis
The journey takes about 5 hours 15 minutes, and with fares starting at just R 497, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 766 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Jefferson Lines ticket prices on this trip start at R 497
Jefferson Lines La Crosse Minneapolis recent customer reviews
Comfy trip. On time. Friendly and competent driver.
Melora P.
Frequently asked questions about travelling from La Crosse, WI to Minneapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from La Crosse to Minneapolis?
The cheapest bus tickets from La Crosse to Minneapolis start at R 497. The average price for this route is around R 497. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from La Crosse to Minneapolis?
The average bus journey time from La Crosse to Minneapolis is 5h 15m, covering a distance of 196 km. The fastest bus gets you there in 2h 55m and is operated by Jefferson Lines.
Which bus companies service the La Crosse to Minneapolis route?
Several major bus companies operate on this route with 18 buses available per day.
What is the earliest and latest departure time for the bus from La Crosse to Minneapolis?
The earliest bus departs from La Crosse to Minneapolis at 13:10. And the latest bus departs at 16:30.
What are the CO₂ emissions for the bus trip from La Crosse to Minneapolis?
A bus trip from La Crosse to Minneapolis produces an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from La Crosse, WI to Minneapolis was searched and found on 17 Feb 2026 with a price of R 481To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Minneapolis as early as possible.
You can expect to pay from R 481 to R 1 375 for a bus ticket from La Crosse, WI to Minneapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 481, which is on 2026-02-20.
