Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Südseite Hauptbahnhof | Lyon (Gerland) | CheapestFastest | ||||
| Bus | Südseite Hauptbahnhof | Lyon (Gerland) | No tags | ||||
| Bus | Südseite Hauptbahnhof | Aéroport LYS | No tags |
Last refresh of the prices: Last Thursday at 5:46 PM CET.
Compare 3 ways to travel from Karlsruhe to Lyon
Among the sustainable travel choices, the Carpool stands out as a good way to reach Lyon. The journey takes about 5 hours 10 minutes and with fares starting at just R 766, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average priceR 426 - R 2 158 | Average duration9h 30m | 11kg CO₂e | ||
Train | Average priceR 3 173 - R 5 711 | Average duration5h 24m | 11kg CO₂e | |
Carpool | Average priceR 766 - R 1 013 | Average duration5h 10m | 19kg CO₂e |
Where are the popular stops in Karlsruhe and Lyon?
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
Stops in Lyon
- A
Lyon Airport
- BRue de Esplanade, 69002 Lyon, France
- C
Lyon
8 Rue de la Paix, 69700 Givors, France - D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France - E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France - FLes Charrières, 69570 Dardilly, France
Compare bus companies
Frequently asked questions about travelling from Karlsruhe to Lyon by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Karlsruhe to Lyon?
The cheapest bus tickets from Karlsruhe to Lyon start at R 426. The average price for this route is around R 640. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Karlsruhe to Lyon?
The average bus journey time from Karlsruhe to Lyon is 9h 30m, covering a distance of 450 km. The fastest bus gets you there in 7h 55m and is operated by FlixBus.
Which bus companies service the Karlsruhe to Lyon route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Karlsruhe to Lyon?
The earliest bus departs from Karlsruhe to Lyon at 00:25. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Karlsruhe to Lyon?
A bus trip from Karlsruhe to Lyon produces an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Karlsruhe to Lyon?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11385 reviews.
Which bus company has the best Wi-Fi from Karlsruhe to Lyon?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Karlsruhe to Lyon?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Karlsruhe to Lyon?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlsruhe to Lyon was searched and found on 07 Feb 2026 with a price of R 435To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Lyon as early as possible.
You can expect to pay from R 435 to R 1 884 for a bus ticket from Karlsruhe to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at R 435, which is on 2026-02-07.
What's the cheapest way to go from Karlsruhe to Lyon?
The Bus is the cheapest travel choice for this destination
