Bus from Buffalo, NY to San Diego, CA, US: Tickets & Timetables

Previously seen journeys

Next departures from Buffalo to San Diego on 5 February
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Niagara Frontier Transportation Authority
UCSD Health La Jolla StationNo tags
FlixBus + Greyhound
Bus
Niagara Frontier Transportation Authority
Balboa ParkNo tags
FlixBus + Greyhound
Bus
Niagara Frontier Transportation Authority
Downtown SD (Seaport)No tags
FlixBus + Greyhound
Bus
Niagara Frontier Transportation Authority
San Diego (Old Town-FlixBus)No tags
Greyhound + FlixBus
Bus
Buffalo (BUF) Airport
Downtown SD (Seaport)No tags

Compare 2 ways to travel from Buffalo to San Diego

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach San Diego. The journey takes about 2 days, 15 hours 14 minutes and with fares starting at just €245, it presents an excellent value for a comfortable ride.

2train per day
2d 15hAverage duration
3527 kmDistance
321kgCO₂ emissions
Average price€196 - €390Average duration3d 8h
88kg CO₂e
Average price€245 - €246Average duration2d 15h
321kg CO₂e

Frequently asked questions about travelling by bus from Buffalo, NY to San Diego, CA, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Buffalo to San Diego?

    The cheapest coach tickets from Buffalo to San Diego start from €196. The average price for this route is around €203. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Buffalo to San Diego?

    The average bus journey time from Buffalo to San Diego is 3d 8h, covering a distance of 3528 km. The fastest bus can take you there in 3d 3h and is operated by Greyhound.

  3. Which bus companies service the Buffalo to San Diego route?

    Several major bus companies operate on this route with 16 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Buffalo to San Diego?

    The earliest bus departs from Buffalo to San Diego at 07:55. And the latest bus departs at 23:20.

  5. What are the CO₂ emissions for the bus trip from Buffalo to San Diego?

    A bus journey from Buffalo to San Diego produces an estimated 88 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Buffalo to San Diego?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87518 reviews.

  7. Which company has the best Wi-Fi from Buffalo to San Diego?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Buffalo to San Diego?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Buffalo to San Diego?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/02
No data
04/02
€195
Today
No data
06/02
No data
07/02
No data
08/02
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09/02
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10/02
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busbud logoThe cheapest trip from Buffalo, NY to San Diego, CA, US was searched and found on 4 Feb 2026 with a price of €195

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to San Diego, CA, US as early as possible.

What's the cheapest way to go from Buffalo, NY to San Diego, CA, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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