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Bus San Nicolas to Santiago del Estero: Trip Overview

Average ticket priceUS$78
Average bus trip duration11h 5m
Number of daily buses2
Earliest bus departure17:45
Distance453 miles
Latest bus departure20:55

San Nicolas to Santiago del Estero Bus

Busbud helps you find a bus from San Nicolas to Santiago del Estero. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from San Nicolas to Santiago del Estero from the most reliable bus companies operating this trip.

Discover how much the bus trip from San Nicolas to Santiago del Estero will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Nicolas - Santiago del Estero

  1. What's the distance between San Nicolas and Santiago del Estero by coach?

    The journey from San Nicolas to Santiago del Estero by coach covers an approximate distance of 453 miles (730 km).

  2. How can I travel from San Nicolas to Santiago del Estero avoiding air travel?

    To travel from San Nicolas to Santiago del Estero without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$56
busbud logoThe cheapest trip from San Nicolas to Santiago del Estero was searched and found on 24 Jun 2025 with a price of US$56

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Nicolas to Santiago del Estero as early as possible.

You can expect to pay from US$56 to US$71 for a bus ticket from San Nicolas to Santiago del Estero based on the last 2 days. You can expect to find the cheapest price for the trip at US$56, which is on 2025-06-24.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Nicolas and Santiago del Estero!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Nicolas to Santiago del Estero, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Nicolas to Santiago del Estero will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from San Nicolas to Santiago del Estero, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to San Nicolas by bus?

Bus from San Nicolas to Santiago del Estero

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