Next departures to San Francisco
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: June 22 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 25 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: June 22 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 24 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 22 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 24 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 22 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 24 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
- Departure time: June 22 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 24 atDestination city: San FranciscoDestination location: Mission St & Fremont StOperated by: AmtrakVehicle: BusDuration:
Last refresh of the prices: Last Sunday at 5:23 AM CDT.
Prices and availability are subject to change.
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Compare 2 ways to go from St Louis to San Francisco
Busbud recommends taking the bus from St Louis to San FranciscoAmong the sustainable travel choices, the bus stands out as a good way to reach San Francisco. The journey takes about 2 days, 1 hour 5 minutes, and with fares starting at just US$150, it presents an excellent value for a comfortable ride.
Train St Louis to San Francisco: Trip Overview
Please note, this information is subject to change
Train companies
Based on 5220 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at US$148
St Louis to San Francisco Train
With Busbud, comparing and booking tickets for a train from St Louis to San Francisco is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make sure you can find a train service from St Louis to San Francisco from the most reliable train companies operating this trip.
From train tickets to high-end trains trip from St Louis to San Francisco, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip St Louis - San Francisco, US
How much does a cheap train ticket from St Louis to San Francisco cost?
The average train ticket price from St Louis to San Francisco is US$307. The best way to find cheap train tickets from St Louis to San Francisco is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from St Louis to San Francisco?
A train trip between St Louis and San Francisco is around 2d 12h, although the fastest train will take about 2d 12h. This is the time it takes to travel the 2806 km that separates the two cities.
How many daily trains are there between St Louis and San Francisco?
The number of trains from St Louis to San Francisco can differ depending on the day of the week. On average, there are 2.3333333333333335. Some trains are direct while others include transferring trains. Simplify your train trip from St Louis to San Francisco by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from St Louis to San Francisco?
When taking the train from St Louis to San Francisco, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St Louis to San Francisco was searched and found on Jun 24, 2025 with a price of US$306To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St Louis to San Francisco, as early as possible.
You can expect to pay from US$306 to US$1,807 for a train ticket from St Louis to San Francisco based on the last 2 days. You can expect to find the cheapest price for the trip at US$306 which is on 2025-06-24.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from St Louis to San Francisco is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Regional train? High-speed train? Whichever train to San Francisco you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between St Louis and San Francisco compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from St Louis to San Francisco.
Did you know?
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date.
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
Top Travelled Train Routes
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