Trains leaving Tuesday
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: June 10 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 13 atDestination city: San DiegoDestination location: Old Town San DiegoOperated by: Amtrak
Vehicle: TrainDuration: - This trip is recommended because it is the: FastestDeparture time: June 10 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 12 atDestination city: San DiegoDestination location: Old Town San DiegoOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 10 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 13 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 10 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 13 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: TrainDuration:
- Departure time: June 10 atDeparture city: St LouisDeparture location: Gateway StationArrival time: June 12 atDestination city: San DiegoDestination location: Santa Fe DepotOperated by: AmtrakVehicle: TrainDuration:
Last refresh of the prices: Last Tuesday at 9:58 AM CDT.
Prices and availability are subject to change.
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Compare 2 ways to go from St Louis to San Diego
Busbud recommends taking the bus from St Louis to San DiegoAmong the sustainable travel choices, the bus stands out as a good way to reach San Diego. The journey takes about 2 days, 3 hours 15 minutes, and with fares starting at just US$116, it presents an excellent value for a comfortable ride.
Train St Louis to San Diego: Trip Overview
Please note, this information is subject to change
Train companies
Based on 5173 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at US$219.00
St Louis to San Diego Train
Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from St Louis to San Diego.
We make sure you can find a train service from St Louis to San Diego from the most reliable train companies operating this trip.
Whether it is train tickets or first class train tickets going to San Diego from St Louis, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions on the trip St Louis - San Diego (CA), US
How much does a cheap train ticket from St Louis to San Diego cost?
The average train ticket price from St Louis to San Diego is US$249. The best way to find cheap train tickets from St Louis to San Diego is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from St Louis to San Diego?
A train trip between St Louis and San Diego is around 2d 8h, although the fastest train will take about 2d 8h. This is the time it takes to travel the 2516 km that separates the two cities.
How many daily trains are there between St Louis and San Diego?
The number of trains from St Louis to San Diego can differ depending on the day of the week. On average, there are 3. Some trains are direct while others include transferring trains. Simplify your train trip from St Louis to San Diego by comparing and selecting the train that fits your travel style and budget on Busbud.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St Louis to San Diego was searched and found on Jun 10, 2025 with a price of US$314To save money and be sure you have the best seat, it's a good idea to buy your train tickets from St Louis to San Diego, as early as possible.
You can expect to pay from US$314 to US$1,417 for a train ticket from St Louis to San Diego based on the last 2 days. You can expect to find the cheapest price for the trip at US$314 which is on 2025-06-10.
About Train Travel
Train Travel Tips
Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between St Louis and San Diego is also a great way to travel to arrive in the city centre and save more time for your stay in San Diego.
Regional train? High-speed train? Whichever train to San Diego you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
By choosing the train between St Louis and San Diego, you emit up to 30 times less CO2 than for the same journey made by plane or car!
Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from St Louis to San Diego.
Did you know?
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.
The first high-speed train line was inaugurated in 1964, in Japan, to connect Tokyo with Osaka. It was during the Olympics that the first passengers travelled aboard the Shinkansen at a speed of 210 km / h.
Top Travelled Train Routes
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