Trains tickets from San Diego, CA, US to Indianapolis

Discover your next train travel journey from San Diego, CA, US to Indianapolis and book online with ease

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TomorrowJul 13
MonJul 14
TueJul 15
WedJul 16
ThuJul 17
FriJul 18
from US$521
SatJul 19
SunJul 20

Next departures to Indianapolis

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 18 at
    Departure city: San Diego
    Departure location: Old Town San Diego
    Arrival time: July 21 at
    Destination city: Indianapolis
    Destination location: Greyhound Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 18 at
    Departure city: San Diego
    Departure location: Old Town San Diego
    Arrival time: July 20 at
    Destination city: Indianapolis
    Destination location: Greyhound Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: July 18 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: July 20 at
    Destination city: Indianapolis
    Destination location: Greyhound Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: July 18 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: July 21 at
    Destination city: Indianapolis
    Destination location: Greyhound Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: July 18 at
    Departure city: San Diego
    Departure location: Santa Fe Depot
    Arrival time: July 21 at
    Destination city: Indianapolis
    Destination location: Greyhound Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Last refresh of the prices: Today at 9:54 AM PDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Diego to Indianapolis

Bus
Average PriceUS$138 - US$278Average Duration2d 8h
72kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$208 - US$542Average Duration2d 9h
261kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from San Diego to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 2 days, 8 hours 55 minutes, and with fares starting at just US$138, it presents an excellent value for a comfortable ride.

20bus per day
2d 8hAverage Duration
US$138Cheapest ticket
72kgCO₂ emissions

Train San Diego, CA, US to Indianapolis: Trip Overview

Please note, this information is subject to change

Average Ticket PriceUS$327
Average train trip duration2d 9h
Number of daily trains6
Earliest train departure2:01pm
Distance2873 km
Latest train departure4:10pm

San Diego to Indianapolis Train

Busbud helps you find a train from San Diego to Indianapolis. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.

We make sure you can find a train service from San Diego to Indianapolis from the most reliable train companies operating this trip.

From train tickets to high-end trains trip from San Diego to Indianapolis, we offer a wide range of train services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Diego, CA, US - Indianapolis

  1. How much does a cheap train ticket from San Diego to Indianapolis cost?

    The average train ticket price from San Diego to Indianapolis is US$327. The best way to find cheap train tickets from San Diego to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the trip from San Diego to Indianapolis?

    A train trip between San Diego and Indianapolis is around 2d 9h, although the fastest train will take about 2d 1h. This is the time it takes to travel the 2876 km that separates the two cities.

  3. How many daily trains are there between San Diego and Indianapolis?

    The number of trains from San Diego to Indianapolis can differ depending on the day of the week. On average, there are 6. Some trains are direct while others include transferring trains. Simplify your train trip from San Diego to Indianapolis by comparing and selecting the train that fits your travel style and budget on Busbud.

  4. Which train companies travel from San Diego to Indianapolis?

    When taking the train from San Diego to Indianapolis, you can travel comfortably and safely with Amtrak.

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-10
No data
07-11
No data
Today
US$362
07-13
No data
07-14
No data
07-15
No data
07-16
US$375
07-17
No data
busbud logoThe cheapest trip from San Diego to Indianapolis was searched and found on Jul 12, 2025 with a price of US$362

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from San Diego to Indianapolis, as early as possible.

You can expect to pay from US$362 to US$1,858 for a train ticket from San Diego to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$375 which is on 2025-07-16.

About Train Travel

Train Travel Tips

There are many train stations in the world, check out the station pages on Busbud to get all information you need.

Regional train? High-speed train? Whichever train to Indianapolis you take, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.

The train emits up to 30x less CO2 for a trip between San Diego and Indianapolis compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.

Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from San Diego to Indianapolis.

Did you know?

The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while travelling more than 17,000 km.

Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

Will you be returning to San Diego, CA, US by train?

Train from Indianapolis to San Diego, CA, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Trains Connecting San Diego

Trains Leaving from San Diego

Popular Trains Connecting Indianapolis

Trains Going to Indianapolis