Next train departures Today, Mar 19 Tomorrow, Mar 20 Sat, Mar 21 Sun, Mar 22 Mon, Mar 23 Tue, Mar 24 Wed, Mar 25 Thu, Mar 26 More dates
Next departures for Syracuse to Buffalo on March 19 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Cheapest Fastest $42 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $47 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $47 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $109 Train 6:59pm
Amtrak Station 2h 43m 9:42pm
Exchange Street Station No tags $47
Next departures for Syracuse to Buffalo on March 20 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 4:02pm
Amtrak Station 2h 32m 6:34pm
Depew Station Cheapest $42 Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Fastest $56 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $62 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $47
Next departures for Syracuse to Buffalo on March 21 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 6:59pm
Amtrak Station 2h 22m 9:21pm
Depew Station Cheapest $42 Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Fastest $49 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $55 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $55
Next departures for Syracuse to Buffalo on March 22 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 6:59pm
Amtrak Station 2h 22m 9:21pm
Depew Station Cheapest $42 Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Fastest $87 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $90 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $55
Next departures for Syracuse to Buffalo on March 23 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Cheapest Fastest $42 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $47 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $47 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $109
Next departures for Syracuse to Buffalo on March 24 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Cheapest Fastest $42 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $47 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $47 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $109
Next departures for Syracuse to Buffalo on March 25 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Cheapest Fastest $42 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $47 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $47 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $109
Next departures for Syracuse to Buffalo on March 26 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Train 12:57pm
Amtrak Station 2h 22m 3:19pm
Depew Station Cheapest Fastest $42 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $47 Train 12:57pm
Amtrak Station 2h 35m 3:32pm
Exchange Street Station No tags $142 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $47 Train 4:02pm
Amtrak Station 2h 53m 6:55pm
Exchange Street Station No tags $109
Last refresh of the prices: Yesterday at 11:44 AM EDT.
View all departures Where are the popular train stations and stops in Syracuse, US and Buffalo, NY? Find cheapest prices for trains Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Buffalo, NY was searched and found on Mar 17, 2026 with a price of $38 To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Syracuse, US to Buffalo, NY, as early as possible.
You can expect to pay from $38 to $760 for a train ticket from Syracuse, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $38 which is on 2026-03-20.
Top Travelled Train Routes People from around the world trust Busbud
Popular train departures from Syracuse Popular train routes to Buffalo Continue your journey from Buffalo 
The cheapest trip from Syracuse, US to Buffalo, NY was searched and found on Mar 17, 2026 with a price of $38
