Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Tupelo (Brothers Quick Stop) | Downtown Gray & Smith | Cheapest | |||||
 | Tupelo (Brothers Quick Stop) | Houston Bus Station | Fastest | |||||
| Tupelo (Brothers Quick Stop) | Houston Bus Station | No tags | |||||
Greyhound Lines, Inc. + FlixBus | Tupelo (Brothers Quick Stop) | Downtown Gray & Smith | No tags | |||||
| Tupelo (Brothers Quick Stop) | Houston Bus Station | No tags |
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Bus Tupelo to Houston, US: Trip Overview
Compare bus companies
Based on 87222 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at US$84
Greyhound Tupelo Houston recent customer reviews
Bus was late bc of the snow storm..But there was no heat and the bus broke down 4x on way to memphis.. The bus driver held all passengers pretty much hostage . Even the lady with her baby that was freezing . We were stuck in a traffic jam not moving for almost an hour.The bus driver should took the inhumane conditions seriously since everyone was freezing with no heat
Alvin J.
Tupelo to Houston Bus
Busbud helps you find a bus from Tupelo to Houston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Tupelo to Houston.
Discover how much the bus trip from Tupelo to Houston will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Frequently asked questions on the trip Tupelo - Houston, US
What is the distance between Tupelo and Houston?
It's about 805 km (499 miles) from Tupelo to Houston.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Houston, US was searched and found on Sep 2, 2025 with a price of US$111To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Houston, US, as early as possible.
You can expect to pay from US$111 to US$293 for a bus ticket from Tupelo to Houston, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$111 which is on 2025-09-02.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tupelo and Houston!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Tupelo to Houston.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Tupelo to Houston will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Tupelo to Houston while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
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Popular Buses Connecting Tupelo
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