Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Southampton | Manchester Airport | Cheapest | ||||
| Bus | Southampton University | Manchester Airport | Fastest | ||||
| Bus | Southampton | Shudehill | No tags | ||||
| Bus | Southampton | Manchester (Moss Lane East) | No tags | ||||
| Bus | Southampton University | Shudehill | No tags |
Last refresh of the prices: Yesterday at 4:13 PM GMT.
Compare 3 ways to go from Southampton to Manchester
Among the sustainable travel choices, the Carpool stands out as a good way to reach Manchester. The journey takes about 4 hours, and with fares starting at just $38, it presents an excellent value for a comfortable ride.
Where are the popular stops in Southampton and Manchester?
Stops in Southampton
- A20 Harbour Parade, Southampton SO15 1BA, UK
- B
Southampton Bus Stop
563 Vincents Walk, Southampton SO14, UK - C
W. Esplanade Bus Station - Southampton
Wyndham Pl, Southampton SO15, UK - D
Bus Stop Queensway
51-55 Above Bar St, Southampton, Southampton SO14 7DZ, UK - E
Southampton Central
Western Esplanade, Southampton SO15 1QJ, UK - F
Ferry Terminal
7 Town Quay, Southampton SO14 2ET, UK
Stops in Manchester
- AShudehill Interchange, Stand G, Manchester M60
- B16 Chorlton St, Manchester M1 3HW, UK
- D
56 Great Bridgewater St
56 Great Bridgewater St, Manchester M1 5LE, UK - E
City of Manchester Stadium
Citylink, Manchester M40 7EP, UK - F
Manchester Coach Station
Manchester Coach Station, Chorlton St., , Manchester M1 3JF, United Kingdom
Compare bus companies
Based on 11989 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $54
Frequently asked questions about travelling from Southampton to Manchester by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Southampton to Manchester?
The cheapest bus tickets from Southampton to Manchester start from $54. The average price for this route is around $72. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Southampton to Manchester?
The average bus travel time from Southampton to Manchester is 12h 25m, covering a distance of 290 km. The quickest bus can get you there in 7h 45m and is operated by FlixBus.
Which bus companies service the Southampton to Manchester route?
Several major bus companies operate on this route with 6 buses available per day.
What are the earliest and latest departure times for the bus from Southampton to Manchester?
The earliest bus departs from Southampton to Manchester at 10:45am. And the latest bus departs at 5:15pm.
What are the CO₂ emissions for the bus trip from Southampton to Manchester?
A bus trip from Southampton to Manchester generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Southampton to Manchester was searched and found on Jan 8, 2026 with a price of $54To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Southampton to Manchester, as early as possible.
You can expect to pay from $54 to $78 for a bus ticket from Southampton to Manchester based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2026-01-14.
