Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Siena Train Station | Milan (San Donato M3) | Cheapest | |||||
| Siena Train Station | Milan (San Donato M3) | Fastest | |||||
 | Siena Train Station | Lampugnano | No tags | |||||
| Siena Train Station | Milan (Malpensa Aeroporto Terminal 1) | No tags | |||||
| Siena Train Station | Lampugnano | No tags |
Accepted payments
Compare 2 ways to go from Siena to Milano
| Average Price | Average Duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average PriceUS$11 - US$122 | Average Duration6h 30m | 8kg CO₂e5 out of 5 stars | CheapestMost eco-friendly | ||
Carpool | Average PriceUS$20 - US$42 | Average Duration3h 50m | 12kg CO₂e4 out of 5 stars | Fastest |
Busbud recommends carpooling from Siena to MilanoAmong the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 3 hours 50 minutes, and with fares starting at just US$20, it presents an excellent value for a comfortable ride.
Bus Siena to Milano: Trip Overview
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Siena to Milano Bus
Busbud helps you find a bus from Siena to Milano. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Siena to Milano.
From cheap bus tickets to more luxurious buses travelling from Siena to Milano, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Siena and Milano?
Frequently asked questions on the trip Siena - Milano
What is the travel distance from Siena to Milano?
The distance between Siena and Milano is around 294 km (182 miles).
What are the departure and arrival locations for buses traveling from Siena to Milano?
Buses traveling this route start their trip at Piazza Gramsci, in Siena, and end it at Lampugnano, in Milano.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Siena to Milano was searched and found on Sep 7, 2025 with a price of US$14To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Milano, as early as possible.
You can expect to pay from US$14 to US$113 for a bus ticket from Siena to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at US$14 which is on 2025-09-07.
Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Siena and Milano!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Siena to Milano.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Siena to Milano that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Siena to Milano.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from Siena to Milano?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting Siena
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Popular Buses Connecting Milano
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