Bus Tickets from Santa Maria, US to San Diego, CA, US

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WedSep 3
from US$81
ThuSep 4
from US$81
FriSep 5
SatSep 6
SunSep 7
MonSep 8
TueSep 9
WedSep 10

Next departures to San Diego

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 4 at
    Departure city: Santa Maria
    Departure location: Nicholson Ave
    Arrival time: September 4 at
    Destination city: San Diego
    Destination location: Santa Fe Depot
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 4 at
    Departure city: Santa Maria
    Departure location: Nicholson Ave
    Arrival time: September 4 at
    Destination city: San Diego
    Destination location: Old Town San Diego
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Santa Maria
    Departure location: Nicholson Ave
    Arrival time: September 4 at
    Destination city: San Diego
    Destination location: Santa Fe Depot
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Santa Maria
    Departure location: Nicholson Ave
    Arrival time: September 4 at
    Destination city: San Diego
    Destination location: Santa Fe Depot
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Santa Maria
    Departure location: Nicholson Ave
    Arrival time: September 4 at
    Destination city: San Diego
    Destination location: Santa Fe Depot
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

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Bus Santa Maria, US to San Diego, CA, US: Trip Overview

Average Ticket PriceUS$81
Average Bus Trip Duration8h 55m
Number of daily buses1
Earliest bus departure8:05pm
Distance390 km
Latest bus departure8:30pm

Santa Maria to San Diego Bus

Busbud helps you find a bus from Santa Maria to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santa Maria to San Diego.

Discover how much the bus trip from Santa Maria to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Santa Maria, US - San Diego, CA, US

  1. How far is Santa Maria from San Diego?

    The distance between Santa Maria and San Diego is approximately 392 km (243 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-30
No data
08-31
US$77
Today
No data
09-02
No data
09-03
US$77
09-04
US$77
09-05
US$77
09-06
No data
busbud logoThe cheapest trip from Santa Maria, US to San Diego, CA, US was searched and found on Aug 31, 2025 with a price of US$77

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria, US to San Diego, CA, US, as early as possible.

You can expect to pay from US$77 to US$98 for a bus ticket from Santa Maria, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$77 which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santa Maria and San Diego!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santa Maria to San Diego.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santa Maria to San Diego will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Maria to San Diego.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Maria, US by bus?

Bus from San Diego, CA, US to Santa Maria, US

Why choose Busbud?

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