Next departures to Los Angeles
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: September 5 atDeparture city: Santa CruzDeparture location: Santa Cruz, CAArrival time: September 6 atDestination city: Los AngelesDestination location: Union StationOperated by: Amtrak
Vehicle: BusDuration: - This trip is recommended because it is the: FastestDeparture time: September 5 atDeparture city: Santa CruzDeparture location: Santa Cruz, CAArrival time: September 5 atDestination city: Los AngelesDestination location: Union StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: September 5 atDeparture city: Santa CruzDeparture location: Santa Cruz, CAArrival time: September 5 atDestination city: Los AngelesDestination location: Union StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: September 5 atDeparture city: Santa CruzDeparture location: Santa Cruz, CAArrival time: September 5 atDestination city: Los AngelesDestination location: Union StationOperated by: AmtrakVehicle: BusDuration:
- Departure time: September 5 atDeparture city: Santa CruzDeparture location: Santa Cruz, CAArrival time: September 6 atDestination city: Los AngelesDestination location: Union StationOperated by: AmtrakVehicle: BusDuration:
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Bus Santa Cruz, US to Los Angeles, US: Trip Overview
Compare bus companies
Based on 5438 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at US$65
Greyhound Santa Cruz Los Angeles recent customer reviews
I was told by the staff at the station that the bus would be at least half an hour late. It was meant to leave at 8.30am. I was there at 8.55am and the bus never came. I was given the wrong information by the attendant which meant that I completely missed the bus.
Vanessa F.
Good but can be slow depending on traffic and it is difficult to nap with all the stops (unless you're a heavy sleeper)
Janet C.
I could not board my bus because the willcall window remained closed an hour after my scheduled departure. The driver didn’t accept my busbud email confirmation and refused boarding without a Greyhound receipt or printed tickets, which I wasn’t able to get because there was no one there at the Greyhound window. I’m disabled and had to buy airfare to get home. Please help me get reimbursed for the breach of contract and ensuing damages. Thanks
Sasha C.
Santa Cruz to Los Angeles Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Cruz to Los Angeles.
Bus service from Santa Cruz to Los Angeles will be provided by the most trusted bus companies.
Discover how much the bus trip from Santa Cruz to Los Angeles will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Santa Cruz and Los Angeles?
Frequently asked questions on the trip Santa Cruz, US - Los Angeles, US
How far is Santa Cruz from Los Angeles?
The distance covered from Santa Cruz to Los Angeles is 473 km (294 miles).
What are the departure and arrival locations for buses traveling from Santa Cruz to Los Angeles?
Buses traveling this route start their trip at Metro Center Bus Station, in Santa Cruz, and end it at Ramirez Street bus stop, in Los Angeles.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Cruz, US to Los Angeles, US was searched and found on Aug 30, 2025 with a price of US$78To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Cruz, US to Los Angeles, US, as early as possible.
You can expect to pay from US$78 to US$292 for a bus ticket from Santa Cruz, US to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$87 which is on 2025-09-02.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Cruz to Los Angeles but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Santa Cruz to Los Angeles, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Santa Cruz to Los Angeles will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Santa Cruz to Los Angeles, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Top travelled bus routes
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