Bus Tickets from San Luis Obispo to Chicago

Find affordable bus tickets from San Luis Obispo to Chicago with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayAug 30
TomorrowAug 31
from US$262
MonSep 1
TueSep 2
WedSep 3
from US$241
ThuSep 4
from US$241
FriSep 5
from US$241
SatSep 6

Next departures to Chicago

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 31 at
    Departure city: San Luis Obispo
    Departure location: San Luis Obispo
    Arrival time: September 3 at
    Destination city: Chicago
    Destination location: Downtown Greyhound Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 31 at
    Departure city: San Luis Obispo
    Departure location: Cal Poly Vista Grande Dining Complex
    Arrival time: September 2 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: San Luis Obispo
    Departure location: Cal Poly Vista Grande Dining Complex
    Arrival time: September 2 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: San Luis Obispo
    Departure location: San Luis Obispo
    Arrival time: September 3 at
    Destination city: Chicago
    Destination location: 537-517 W. Jackson Blvd
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 31 at
    Departure city: San Luis Obispo
    Departure location: Cal Poly Vista Grande Dining Complex
    Arrival time: September 2 at
    Destination city: Chicago
    Destination location: Chicago (Union Station), IL
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from San Luis Obispo to Chicago

Bus
Average PriceUS$231 - US$351Average Duration2d 13h
74kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$517 - US$517Average Duration2d 6h
268kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from San Luis Obispo to Chicago

Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 2 days, 13 hours 25 minutes, and with fares starting at just US$231, it presents an excellent value for a comfortable ride.

2bus per day
2d 13hAverage Duration
US$231Cheapest ticket
74kgCO₂ emissions

Bus San Luis Obispo to Chicago: Trip Overview

Average Ticket PriceUS$256
Average Bus Trip Duration2d 13h
Number of daily buses2
Earliest bus departure12:55pm
Distance2942 km
Latest bus departure4:30pm

San Luis Obispo to Chicago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Luis Obispo to Chicago.

We make it our job to connect you with the most dependable bus companies that cover bus service from San Luis Obispo to Chicago.

From cheap bus tickets to more luxurious buses travelling from San Luis Obispo to Chicago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Luis Obispo - Chicago

  1. How far is San Luis Obispo from Chicago?

    It's about 2943 km (1825 miles) from San Luis Obispo to Chicago.

  2. What are the departure and arrival locations for buses traveling from San Luis Obispo to Chicago?

    Buses departing from AMTRAK Station in San Luis Obispo will take you to Downtown Greyhound Station in Chicago.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-28
US$191
08-29
No data
Today
No data
08-31
US$296
09-01
No data
09-02
No data
09-03
US$231
09-04
US$231
busbud logoThe cheapest trip from San Luis Obispo to Chicago was searched and found on Aug 28, 2025 with a price of US$191

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Luis Obispo to Chicago, as early as possible.

You can expect to pay from US$191 to US$1,398 for a bus ticket from San Luis Obispo to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$231 which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Luis Obispo to Chicago but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from San Luis Obispo to Chicago.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Luis Obispo to Chicago that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from San Luis Obispo to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from San Luis Obispo to Chicago?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to San Luis Obispo by bus?

Bus from Chicago to San Luis Obispo

You can also go to Chicago by train

Train from San Luis Obispo to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting San Luis Obispo

Buses Leaving from San Luis Obispo

Buses Going to San Luis Obispo

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago