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- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 7 atDeparture city: San DiegoDeparture location: Greyhound Bus StopArrival time: June 10 atDestination city: CharlestonDestination location: Charleston Bus StationOperated by: Greyhound Lines, Inc.
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Last refresh of the prices: Last Tuesday at 10:00 PM PDT.
Prices and availability are subject to change.
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Bus San Diego to Charleston: Trip Overview
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San Diego to Charleston Bus
Busbud helps you find a bus from San Diego to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from San Diego to Charleston will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Charleston from San Diego, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in San Diego and Charleston?
Frequently asked questions on the trip San Diego (CA), US - Charleston (WV), US
How long is the trip from San Diego to Charleston by bus?
The trip from San Diego to Charleston will take on average 2d 12h. The fastest bus on this trip will get to Charleston in 2d 11h
What is the travel distance from San Diego to Charleston?
It's about 3259 km (2021 miles) from San Diego to Charleston.
What are the departure and arrival locations for buses traveling from San Diego to Charleston?
Buses departing from Mission Valley Sheraton in San Diego will take you to Charleston Greyhound Bus Station in Charleston.
What is the cheapest way to travel from San Diego to Charleston?
Taking the bus is the most budget-friendly option to travel from San Diego to Charleston. With a starting ticket price of US$260, this bus becomes your top pick for this journey.
How much does the bus ticket cost from San Diego to Charleston?
You can expect to pay around US$308 for the bus ride from San Diego to Charleston.
Is there an overnight bus from San Diego to Charleston?
Yes! If you're heading from San Diego to Charleston, you'll find buses departing until 2:00pm and arriving the next day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Diego to Charleston was searched and found on Jun 7, 2025 with a price of US$252To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego to Charleston, as early as possible.
You can expect to pay from US$252 to US$288 for a bus ticket from San Diego to Charleston based on the last 2 days. You can expect to find the cheapest price for the trip at US$252 which is on 2025-06-07.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Charleston!
Much more than a mere vehicle taking you from San Diego to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from San Diego to Charleston.
Tune out to the fine sounds of your best music playlist on your bus trip from San Diego to Charleston while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
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