Next bus departures Today, Mar 19 Tomorrow, Mar 20 Sat, Mar 21 Sun, Mar 22 More dates
Next departures for Rome to Lyon on March 19 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 1:00pm
Rome Tiburtina Bus Station 15h 55m 4:55am
Lyon Avenue Tony Garnier Cheapest $52 Bus 1:05pm
Rome Anagnina 14h 45m 3:50am
Lyon (Gerland) Fastest $120 Bus 8:50am
Rome Tiburtina Bus Station 14h 55m 11:45pm
Lyon (Gerland) No tags $112 Bus 1:00pm
Rome Tiburtina Bus Station 15h 55m 4:55am
Lyon Avenue Tony Garnier No tags $72 Bus 12:20pm
Rome Tiburtina Bus Station 18h 10m 6:30am
Lyon (Gerland) No tags $142
Next departures for Rome to Lyon on March 20 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 9:45pm
Rome Tiburtina Bus Station 15h 10m 12:55pm
Lyon Avenue Tony Garnier Cheapest $54 Bus 7:00am
Rome Tiburtina Bus Station 14h 30m 9:30pm
Lyon Avenue Tony Garnier Fastest $98 Bus 7:00am
Rome Tiburtina Bus Station 14h 30m 9:30pm
Lyon Avenue Tony Garnier No tags $108 Bus 8:00am
Rome Tiburtina Bus Station 16h 25m 12:25am
Lyon Avenue Tony Garnier No tags $56 Bus 8:00am
Rome Tiburtina Bus Station 16h 25m 12:25am
Lyon Avenue Tony Garnier No tags $75
Next departures for Rome to Lyon on March 21 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 1:00pm
Rome Tiburtina Bus Station 15h 55m 4:55am
Lyon Avenue Tony Garnier Cheapest $52 Bus 7:00am
Rome Tiburtina Bus Station 14h 30m 9:30pm
Lyon Avenue Tony Garnier Fastest $54 Bus 7:00am
Rome Tiburtina Bus Station 14h 30m 9:30pm
Lyon Avenue Tony Garnier No tags $64 Bus 8:00am
Rome Tiburtina Bus Station 16h 25m 12:25am
Lyon Avenue Tony Garnier No tags $72 Bus 8:00am
Rome Tiburtina Bus Station 16h 25m 12:25am
Lyon Avenue Tony Garnier No tags $91
Next departures for Rome to Lyon on March 22 Operated by Vehicle type Departure time Departure location Trip duration Arrival time Arrival location Recommended Price and booking link Bus 8:00am
Rome Tiburtina Bus Station 16h 25m 12:25am
Lyon Avenue Tony Garnier Cheapest $68 Bus 7:00am
Rome Tiburtina Bus Station 14h 30m 9:30pm
Lyon Avenue Tony Garnier Fastest $130 Bus 12:10am
Rome Tiburtina Bus Station 16h 15m 4:25pm
Lyon (Gerland) No tags $164 Bus 7:00am
Rome Tiburtina Bus Station 14h 30m 9:30pm
Lyon Avenue Tony Garnier No tags $140 Bus 12:15am
Rome Tiburtina Bus Station 20h 55m 9:10pm
Lyon (Gerland) No tags $173
Last refresh of the prices: Yesterday at 8:15 PM CET.
View all departures Where are the popular stops in Rome and Lyon? Stops in Rome D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy Map
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy Map
Stops in Lyon B
Perrache
Rue de Esplanade, 69002 Lyon, France C
Lyon
8 Rue de la Paix, 69700 Givors, France Map
D
Quai de Saoune
4 Cours de Verdun Rambaud, 69002 Lyon, France Map
E
Villeurbanne INSA
20 Avenue Albert Einstein, 69100 Villeurbanne, France Map
Find cheapest prices for buses Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Rome to Lyon was searched and found on Mar 24, 2026 with a price of $42 To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rome to Lyon, as early as possible.
You can expect to pay from $42 to $260 for a bus ticket from Rome to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $42 which is on 2026-03-24.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
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