Bus Tickets from Philadelphia (PA) to Knoxville (TN)

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TodayJun 15
TomorrowJun 16
TueJun 17
WedJun 18
from US$108
ThuJun 19
from US$86
FriJun 20
from US$89
SatJun 21
SunJun 22

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 18 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: June 18 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Philadelphia
    Departure location: Schuylkill & Walnut
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 18 at
    Departure city: Philadelphia
    Departure location: Cherry Hill Mall
    Arrival time: June 19 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 11:17 PM EDT.

Prices and availability are subject to change.

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Bus Philadelphia to Knoxville: Trip Overview

Average Ticket PriceUS$104
Average Bus Trip Duration21h 50m
Number of daily buses6
Earliest bus departure1:55am
Distance881 km
Latest bus departure8:45pm

Philadelphia to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Philadelphia to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Knoxville.

From cheap bus tickets to more luxurious buses travelling from Philadelphia to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Philadelphia (PA) - Knoxville (TN)

  1. How long is the trip from Philadelphia to Knoxville by bus?

    The trip from Philadelphia to Knoxville will take on average 21h 50m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 16h 10m.

  2. What is the travel distance from Philadelphia to Knoxville?

    The distance between Philadelphia and Knoxville is around 888 km (551 miles).

  3. What are the departure and arrival locations for buses traveling from Philadelphia to Knoxville?

    Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at 100 Kirkwood St, in Knoxville.

  4. What is the cheapest way to travel from Philadelphia to Knoxville?

    If you're on a budget, consider traveling by bus to Knoxville from Philadelphia; it tends to be more affordable. The ticket price for this bus starts at US$74, making this your best choice for this trip.

  5. How much does the bus ticket cost from Philadelphia to Knoxville?

    Taking the bus from Philadelphia to Knoxville costs on average US$104.

  6. Is there an overnight bus from Philadelphia to Knoxville?

    Yes! Catch buses leaving from Philadelphia until 8:45pm and reaching Knoxville on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-13
No data
06-14
US$61
Today
US$105
06-16
US$76
06-17
No data
06-18
US$106
06-19
US$79
06-20
US$81
busbud logoThe cheapest trip from Philadelphia to Knoxville was searched and found on Jun 14, 2025 with a price of US$61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to Knoxville, as early as possible.

You can expect to pay from US$61 to US$114 for a bus ticket from Philadelphia to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$76 which is on 2025-06-16.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Philadelphia to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Philadelphia to Knoxville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Philadelphia to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to Knoxville

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