Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Bus Palermo | Siena Train Station | CheapestFastest | ||||
| Bus | Terminal Bus Palermo | Siena Train Station | No tags | ||||
| Bus | Terminal Bus Palermo | Viale Toselli (Penny Market) | No tags |
Last refresh of the prices: Last Tuesday at 9:04 AM CET.
Compare 2 ways to go from Palermo to Siena
Among the sustainable travel choices, the carpool stands out as a good way to reach Siena. The journey takes about 13 hours, and with fares starting at just $101, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$81 - $229 | Average Duration18h 5m | 15kg CO₂e | ||
Carpool | Average Price$101 - $101 | Average Duration13h | 25kg CO₂e |
Where are the popular stops in Palermo and Siena?
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Stops in Siena
- APiazza Antonio Gramsci, 53100 Siena SI, Italy
- B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Compare bus companies
Based on 11785 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $81
Frequently asked questions about travelling from Palermo to Siena by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Palermo to Siena?
The cheapest bus tickets from Palermo to Siena start from $81. The average price for this route is around $137. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Palermo to Siena?
The average bus travel time from Palermo to Siena is 18h 5m, covering a distance of 606 km. The quickest bus can get you there in 16h 20m and is operated by FlixBus.
Which bus companies service the Palermo to Siena route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Palermo to Siena?
The earliest bus departs from Palermo to Siena at 3:25pm. And the latest bus departs at 5:25pm.
What are the CO₂ emissions for the bus trip from Palermo to Siena?
A bus trip from Palermo to Siena generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Palermo to Siena was searched and found on Dec 27, 2025 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Siena, as early as possible.
You can expect to pay from $121 to $200 for a bus ticket from Palermo to Siena based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2025-12-30.
