Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Indianapolis Northeast | Cheapest | ||||
 | Bus | Greyhound Station | Indianapolis Bus Station | Fastest | ||||
| Bus | Greyhound Station | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Greyhound Station | Downtown Transit Center | No tags | ||||
| Bus | Greyhound Station | Indianapolis Bus Station | No tags |
Last refresh of the prices: Today at 12:06 PM CST.
Get from Mobile to Indianapolis
The journey takes about 20 hours 20 minutes, and with fares starting at just $188, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mobile and Indianapolis?
Compare bus companies
Based on 87453 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $188
Greyhound Lines, Inc. Mobile Indianapolis recent customer reviews
Seats are small. Our driver never showed up for the last of our trip. 5 hour wait for a new driver.
Becky B.
Frequently asked questions about travelling from Mobile to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mobile to Indianapolis?
The cheapest bus tickets from Mobile to Indianapolis start from $188. The average price for this route is around $255. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mobile to Indianapolis?
The average bus travel time from Mobile to Indianapolis is 20h 20m, covering a distance of 1027 km. The quickest bus can get you there in 19h 10m and is operated by Greyhound.
Which bus companies service the Mobile to Indianapolis route?
Several major bus companies operate on this route with 6 buses available per day.
What are the earliest and latest departure times for the bus from Mobile to Indianapolis?
The earliest bus departs from Mobile to Indianapolis at 12:05am. And the latest bus departs at 3:55pm.
What are the CO₂ emissions for the bus trip from Mobile to Indianapolis?
A bus trip from Mobile to Indianapolis generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mobile to Indianapolis was searched and found on Dec 27, 2025 with a price of $289To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mobile to Indianapolis, as early as possible.
You can expect to pay from $289 to $293 for a bus ticket from Mobile to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $289 which is on 2025-12-27.
