Bus Tickets from Medford (OR) to Santa Rosa (CA), US

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TodayMay 30
from US$151
TomorrowMay 31
SunJun 1
MonJun 2
TueJun 3
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FriJun 6

Next departures to Santa Rosa

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 30 at
    Departure city: Medford
    Departure location: MFR Airport
    Arrival time: May 31 at
    Destination city: Santa Rosa
    Destination location: Santa Rosa, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 30 at
    Departure city: Medford
    Departure location: MFR Airport
    Arrival time: May 31 at
    Destination city: Santa Rosa
    Destination location: Santa Rosa, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 30 at
    Departure city: Medford
    Departure location: Front Street Station
    Arrival time: May 31 at
    Destination city: Santa Rosa
    Destination location: Santa Rosa, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 30 at
    Departure city: Medford
    Departure location: Front Street Station
    Arrival time: May 31 at
    Destination city: Santa Rosa
    Destination location: Santa Rosa, CA
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 9:46 PM PDT.

Prices and availability are subject to change.

Accepted payments

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Bus Medford to Santa Rosa: Trip Overview

Average Ticket PriceUS$105
Average Bus Trip Duration18h 45m
Number of daily buses2
Earliest bus departure4:40pm
Distance435 km
Latest bus departure5:50pm

Medford to Santa Rosa Bus

Busbud helps you find a bus from Medford to Santa Rosa. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Medford to Santa Rosa will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Medford to Santa Rosa, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Medford (OR) - Santa Rosa (CA), US

  1. How long is the trip from Medford to Santa Rosa by bus?

    The bus ride from Medford to Santa Rosa takes 18h 45m, on average. The fastest bus on this trip will get to Santa Rosa in 18h 45m

  2. What is the travel distance from Medford to Santa Rosa?

    Medford and Santa Rosa are 429 km (266 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Medford to Santa Rosa?

    Buses departing from Front Street Station in Medford will take you to Santa Rosa Bus Station in Santa Rosa.

  4. What is the cheapest way to get from Medford to Santa Rosa?

    Taking the bus is the cheapest option to travel from Medford to Santa Rosa. The ticket price for this bus starts at US$105, making this your best choice for this trip.

  5. How much does the bus ticket cost from Medford to Santa Rosa?

    The bus from Medford to Santa Rosa will cost you US$105, on average.

  6. Is there an overnight bus from Medford to Santa Rosa?

    Yes! If you're heading from Medford to Santa Rosa, you'll find buses departing until 5:50pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-28
No data
05-29
US$144
Today
US$144
05-31
No data
06-01
No data
06-02
No data
06-03
No data
06-04
No data
busbud logoThe cheapest trip from Medford to Santa Rosa was searched and found on May 29, 2025 with a price of US$144

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Medford to Santa Rosa, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Medford and Santa Rosa!

Much more than a mere vehicle taking you from Medford to Santa Rosa, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Medford to Santa Rosa that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Medford to Santa Rosa.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Medford by bus?

Bus from Medford to Santa Rosa

You can also go to Santa Rosa by train

Train from Medford to Santa Rosa

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