Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | Cheapest | |||||
| Heinrich-von-Stephan-Straße 4-6 | Prague (Na Knížecí) | Fastest | |||||
| Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | No tags | |||||
Flixtrain + Flixbus | Mannheim Hauptbahnhof | PRG Airport | No tags | |||||
| Heinrich-von-Stephan-Straße 4-6 | Prague (Central Bus Station Florenc) | No tags |
Accepted payments
Compare 3 ways to go from Mannheim to Prague
| Average Price | Average Duration | CO₂ emissions | |||
|---|---|---|---|---|---|
| Average PriceUS$38 - US$134 | Average Duration7h 35m | 11kg CO₂e5 out of 5 stars | |||
| Average PriceUS$38 - US$203 | Average Duration7h 51m | 10kg CO₂e5 out of 5 stars | Most eco-friendly | ||
Carpool | Average PriceUS$37 - US$58 | Average Duration5h 10m | 18kg CO₂e4 out of 5 stars | CheapestFastest |
Busbud recommends carpooling from Mannheim to PragueAmong the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 5 hours 10 minutes, and with fares starting at just US$37, it presents an excellent value for a comfortable ride.
Bus Mannheim to Prague: Trip Overview
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Mannheim to Prague Bus
Busbud helps you find a bus from Mannheim to Prague. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Mannheim to Prague.
Discover how much the bus trip from Mannheim to Prague will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Mannheim and Prague?
Frequently asked questions on the trip Mannheim - Prague
What is the distance between Mannheim and Prague?
It's about 432 km (268 miles) from Mannheim to Prague.
What are the departure and arrival locations for buses traveling from Mannheim to Prague?
Buses departing from ZOB in Mannheim will take you to PRG Airport in Prague.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Prague was searched and found on Aug 24, 2025 with a price of US$31To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Prague, as early as possible.
You can expect to pay from US$31 to US$71 for a bus ticket from Mannheim to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$31 which is on 2025-08-24.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mannheim and Prague!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Mannheim to Prague.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Mannheim to Prague will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Mannheim to Prague while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top travelled bus routes
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.