Bus Tickets from Lyon to Prague

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TodayJul 18
TomorrowJul 19
from US$77
SunJul 20
MonJul 21
TueJul 22
WedJul 23
ThuJul 24
FriJul 25

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 19 at
    Departure city: Lyon
    Departure location: Lyon - Perrache Bus Station
    Arrival time: July 19 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 19 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: July 20 at
    Destination city: Prague
    Destination location: Prague (Na Knížecí)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: July 19 at
    Departure city: Lyon
    Departure location: Lyon - Perrache Bus Station
    Arrival time: July 19 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: July 19 at
    Departure city: Lyon
    Departure location: de Perrache - Galerie A
    Arrival time: July 20 at
    Destination city: Prague
    Destination location: Florenc
    Operated by: RegioJetRegioJet
    Vehicle: BusDuration:
  • Departure time: July 19 at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: July 20 at
    Destination city: Prague
    Destination location: Prague (Central Bus Station Florenc)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 10:07 PM CEST.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Lyon to Prague: Trip Overview

Average Ticket PriceUS$87
Average Bus Trip Duration18h 45m
Number of daily buses7
Earliest bus departure1:20am
Distance863 km
Latest bus departure10:00pm

Lyon to Prague Bus

With Busbud, comparing and booking tickets for a bus from Lyon to Prague is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Lyon to Prague from the most reliable bus companies operating this trip.

Discover how much the bus trip from Lyon to Prague will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Lyon - Prague

  1. How much does a bus ticket from Lyon to Prague cost?

    The bus ticket price from Lyon to Prague starts at US$59. The best way to find cheap bus tickets from Lyon to Prague is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Lyon to Prague?

    The average travel time between Lyon and Prague is around 18h 45m, although the fastest bus will take about 14h 40m.This is the time it takes to travel the 861 km that separates the two cities.

  3. How many daily bus connections are there between Lyon and Prague?

    The number of buses from Lyon to Prague can differ depending on the day of the week. On average, there are 7 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Lyon to Prague by comparing and selecting the bus that fits you travel style and budget on Busbud.

  4. Which bus companies travel from Lyon to Prague?

    When taking the bus from Lyon to Prague, you can travel comfortably and safely with FlixBus, BlaBlaCar Bus, RegioJet.

  5. What are the departure and arrival stations when taking the bus from Lyon to Prague?

    Buses travelling between Lyon and Prague leave from Perrache or Lyon Airport and arrive at Florenc, PRG Airport, Černý Most.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-16
US$77
07-17
US$85
Today
US$58
07-19
US$72
07-20
US$104
07-21
US$73
07-22
US$72
07-23
US$73
busbud logoThe cheapest trip from Lyon to Prague was searched and found on Jul 18, 2025 with a price of US$58

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Prague, as early as possible.

You can expect to pay from US$58 to US$116 for a bus ticket from Lyon to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$72 which is on 2025-07-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Lyon to Prague.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Lyon to Prague, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Prague will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lyon to Prague, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Lyon by bus?

Bus from Lyon to Prague

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