Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Isernia | Milan (Malpensa Aeroporto Terminal 1) | Cheapest | ||||
| Bus | Isernia | Milan (San Donato M3) | Fastest | ||||
| Bus | Isernia | Milan (Malpensa Aeroporto Terminal 1) | No tags | ||||
| Bus | Isernia | Aeroporto Malpensa T2 | No tags | ||||
| Bus | Isernia | Aeroporto Malpensa T2 | No tags |
Last refresh of the prices: Last Monday at 3:06 PM CET.
Compare 2 ways to go from Isernia to Milano
Among the sustainable travel choices, the bus stands out as a good way to reach Milano. The journey takes about 16 hours 59 minutes, and with fares starting at just $76, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$76 - $182 | Average Duration16h 59m | 15kg CO₂e | ||
Carpool | Average Price$76 - $76 | Average Duration6h 30m | 25kg CO₂e |
Where are the popular stops in Isernia and Milano?
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- CVia Giulio Natta, 228, 20151 Milano, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Compare bus companies
Based on 11711 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $76
Frequently asked questions about travelling from Isernia to Milano by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Isernia to Milano?
The cheapest bus tickets from Isernia to Milano start from $76. The average price for this route is around $102. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Isernia to Milano?
The average bus travel time from Isernia to Milano is 16h 59m, covering a distance of 596 km. The quickest bus can get you there in 13h and is operated by FlixBus.
Which bus companies service the Isernia to Milano route?
Several major bus companies operate on this route with 12 buses available per day.
What are the earliest and latest departure times for the bus from Isernia to Milano?
The earliest bus departs from Isernia to Milano at 11:25am. And the latest bus departs at 5:01pm.
What are the CO₂ emissions for the bus trip from Isernia to Milano?
A bus trip from Isernia to Milano generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Isernia to Milano was searched and found on Dec 24, 2025 with a price of $76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Isernia to Milano, as early as possible.
You can expect to pay from $76 to $177 for a bus ticket from Isernia to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2025-12-26.
