Bus Tickets from Indianapolis to Panama City, US

Find affordable bus tickets from Indianapolis to Panama City, US with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 5
from US$144
TomorrowJun 6
SatJun 7
SunJun 8
MonJun 9
TueJun 10
WedJun 11
ThuJun 12

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 5 at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: June 7 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 5 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: June 6 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 5 at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: June 6 at
    Destination city: Panama City
    Destination location: Panama City Beach Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 5:00 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Indianapolis to Panama City: Trip Overview

Average Ticket PriceUS$148
Average Bus Trip Duration1d 2h
Number of daily buses3
Earliest bus departure11:25am
Distance1065 km
Latest bus departure11:30pm

Indianapolis to Panama City Bus

Busbud helps you find a bus from Indianapolis to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Indianapolis to Panama City from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Panama City from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - Panama City, US

  1. How long does it take to get to Panama City from Indianapolis by bus?

    The typical travel time from Indianapolis to Panama City by bus is around 1d 2h. The fastest bus on this trip will get to Panama City in 22h 50m

  2. What is the distance between Indianapolis and Panama City?

    The distance covered from Indianapolis to Panama City is 1071 km (664 miles).

  3. What are the departure and arrival locations for buses traveling from Indianapolis to Panama City?

    Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Panama City Greyhound Bus Station, in Panama City.

  4. What is the cheapest way to go from Indianapolis to Panama City?

    Taking the bus is the most budget-friendly option to travel from Indianapolis to Panama City. With a starting ticket price of US$97, this bus becomes your top pick for this journey.

  5. How much is the bus from Indianapolis to Panama City?

    The bus fare from Indianapolis to Panama City is approximately US$148.

  6. Is it possible to travel by overnight bus from Indianapolis to Panama City?

    Yes! Catch buses leaving from Indianapolis until 11:30pm and reaching Panama City on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-03
No data
06-04
US$132
Today
US$177
06-06
No data
06-07
No data
06-08
No data
06-09
No data
06-10
No data
busbud logoThe cheapest trip from Indianapolis to Panama City was searched and found on Jun 4, 2025 with a price of US$132

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Panama City, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Panama City!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to Panama City, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Panama City.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Panama City.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Panama City

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis

Popular Buses Connecting Panama City

Buses Leaving from Panama City

Buses Going to Panama City