Next departures to Buffalo
One passenger / one way
- This trip is recommended because it is the: Cheapest
- This trip is recommended because it is the: Fastest
- Departure time: June 25 atDeparture city: IndianapolisDeparture location: Greyhound Amtrak StationArrival time: June 26 atDestination city: BuffaloDestination location: Depew StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: June 25 atDeparture city: IndianapolisDeparture location: Indianapolis Bus StationArrival time: June 26 atDestination city: BuffaloDestination location: Niagara Frontier Transportation AuthorityOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Last Wednesday at 11:11 AM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Indianapolis to Buffalo
Busbud recommends taking the bus from Indianapolis to BuffaloAmong the sustainable travel choices, the bus stands out as a good way to reach Buffalo. The journey takes about 17 hours 45 minutes, and with fares starting at just US$96, it presents an excellent value for a comfortable ride.
Bus Indianapolis to Buffalo: Trip Overview
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Indianapolis to Buffalo Bus
With Busbud, comparing and booking tickets for a bus from Indianapolis to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Buffalo.
Discover how much the bus trip from Indianapolis to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Indianapolis and Buffalo?
Frequently asked questions on the trip Indianapolis - Buffalo, NY
What is the travel distance from Indianapolis to Buffalo?
The distance covered from Indianapolis to Buffalo is 701 km (435 miles).
What are the departure and arrival locations for buses traveling from Indianapolis to Buffalo?
Buses traveling this route start their trip at Greyhound Amtrak Station, in Indianapolis, and end it at Buffalo Airport, in Buffalo.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Buffalo was searched and found on Jun 25, 2025 with a price of US$95To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Buffalo, as early as possible.
You can expect to pay from US$95 to US$1,498 for a bus ticket from Indianapolis to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$95 which is on 2025-06-25.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Indianapolis to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Buffalo.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Buffalo will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to Buffalo while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Indianapolis to Buffalo?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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