Bus Tickets from Houston, US to Des Moines

Find affordable bus tickets from Houston, US to Des Moines with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: October 4 at
    Departure city: Houston
    Departure location: Hillcroft Ave & Southwest Freeway
    Arrival time: October 7 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: Greyhound + Valley Transit + FlixBus
    Greyhound + Valley Transit + FlixBus
    Vehicle: BusDuration:
  • Departure time: October 4 at
    Departure city: Houston
    Departure location: Houston Bus Station
    Arrival time: October 6 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: October 4 at
    Departure city: Houston
    Departure location: Downtown Gray & Smith
    Arrival time: October 6 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: October 4 at
    Departure city: Houston
    Departure location: Houston Uptown/Upper Kirby
    Arrival time: October 6 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:
  • Departure time: October 4 at
    Departure city: Houston
    Departure location: Baytown, 6800 Thompson Rd
    Arrival time: October 7 at
    Destination city: Des Moines
    Destination location: Des Moines (Subway)
    Operated by: FlixBus + Greyhound
    FlixBus + Greyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Houston, US to Des Moines: Trip Overview

Average Ticket PriceUS$231
Average Bus Trip Duration1d 19h
Number of daily buses8
Earliest bus departure2:00am
Distance1328 km
Latest bus departure11:20pm

Houston to Des Moines Bus

With Busbud, comparing and booking tickets for a bus from Houston to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Houston to Des Moines from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Houston to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Houston, US - Des Moines

  1. What is the distance between Houston and Des Moines?

    The distance between Houston and Des Moines is around 1328 km (823 miles).

  2. What are the departure and arrival locations for buses traveling from Houston to Des Moines?

    Buses traveling this route start their trip at Hillcroft Ave & Southwest Freeway, in Houston, and end it at Jefferson/Trailways Depot, in Des Moines.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-28
No data
08-29
US$215
Today
US$205
08-31
No data
09-01
No data
09-02
No data
09-03
No data
09-04
US$215
busbud logoThe cheapest trip from Houston, US to Des Moines was searched and found on Aug 30, 2025 with a price of US$205

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Houston, US to Des Moines, as early as possible.

You can expect to pay from US$205 to US$239 for a bus ticket from Houston, US to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$215 which is on 2025-09-04.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Houston to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Houston to Des Moines, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Houston to Des Moines that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Houston to Des Moines.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Houston, US by bus?

Bus from Des Moines to Houston, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Houston

Buses Leaving from Houston

Buses Going to Houston

Popular Buses Connecting Des Moines

Buses Leaving from Des Moines

Buses Going to Des Moines