Bus Tickets from Harrisburg to Winston-Salem

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Compare 2 ways to go from Harrisburg to Winston-Salem

Average PriceUS$159 - US$190Average Duration18h 15m
14kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average PriceUS$271 - US$271Average Duration14h 35m
50kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Harrisburg to Winston-Salem

Among the sustainable travel choices, the train stands out as a good way to reach Winston-Salem. The journey takes about 14 hours 35 minutes, and with fares starting at just US$271, it presents an excellent value for a comfortable ride.

2train per day
14h 35mAverage Duration
US$271Cheapest ticket
50kgCO₂ emissions

Bus Harrisburg to Winston-Salem: Trip Overview

Average Ticket PriceUS$168
Average Bus Trip Duration18h 15m
Number of daily buses4
Earliest bus departure3:05am
Distance548 km
Latest bus departure9:10pm

Harrisburg to Winston-Salem Bus

Busbud helps you find a bus from Harrisburg to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Harrisburg to Winston-Salem will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Harrisburg to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Harrisburg - Winston-Salem

  1. How long is the trip from Harrisburg to Winston-Salem by bus?

    The bus ride from Harrisburg to Winston-Salem takes 18h 15m, on average. For the shortest travel time, select the fastest bus available, which will take you to Winston-Salem in about 12h 55m.

  2. What is the travel distance from Harrisburg to Winston-Salem?

    Harrisburg and Winston-Salem are 550 km (341 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Harrisburg to Winston-Salem?

    Buses departing from Harrisburg Bieber Greyhound Station in Harrisburg will take you to Winston Salem Greyhound Bus Station in Winston-Salem.

  4. What is the cheapest way to get from Harrisburg to Winston-Salem?

    The least expensive way to go from Harrisburg to Winston-Salem would be going by bus. With a starting ticket price of US$159, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Harrisburg to Winston-Salem?

    The bus from Harrisburg to Winston-Salem will cost you US$168, on average.

  6. Is there an overnight bus from Harrisburg to Winston-Salem?

    Yes! If you're heading from Harrisburg to Winston-Salem, you'll find buses departing until 9:10pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$72
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busbud logoThe cheapest trip from Harrisburg to Winston-Salem was searched and found on Jun 4, 2025 with a price of US$72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Winston-Salem, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Harrisburg and Winston-Salem!

Much more than a mere vehicle taking you from Harrisburg to Winston-Salem, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Harrisburg to Winston-Salem that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Harrisburg to Winston-Salem.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Harrisburg to Winston-Salem?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Harrisburg by bus?

Bus from Harrisburg to Winston-Salem

You can also go to Winston-Salem by train

Train from Harrisburg to Winston-Salem

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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