Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | 1116 Woodruff Rd | Durham Greyhound Bus Station | Cheapest | ||||
 | Bus | #2890 Laurens Rd | BP Gas Station | Fastest | ||||
| Bus | #2890 Laurens Rd | BP Gas Station | No tags | ||||
| Bus | 1116 Woodruff Rd | Durham Greyhound Bus Station | No tags |
Last refresh of the prices: Yesterday at 9:16 AM EST.
Compare 2 ways to go from Greenville to Durham
Among the sustainable travel choices, the bus stands out as a good way to reach Durham. The journey takes about 4 hours 37 minutes, and with fares starting at just $58, it presents an excellent value for a comfortable ride.
Where are the popular stops in Greenville and Durham?
Stops in Greenville
- A
Guadalajara Supermarket Bus Stop
2803 White Horse Rd, Greenville, SC 29611 - B
Greenville Bus Station
9 Hendrix DR, Greenville, SC 29607
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Compare bus companies
Frequently asked questions about travelling from Greenville, SC to Durham, NC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Greenville to Durham?
The cheapest bus tickets from Greenville to Durham start from $58. The average price for this route is around $79. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Greenville to Durham?
The average bus travel time from Greenville to Durham is 4h 37m, covering a distance of 349 km. The quickest bus can get you there in 4h 28m and is operated by Tornado Bus.
Which bus companies service the Greenville to Durham route?
Several major bus companies operate on this route with 9 buses available per day, including services from Wanda Coach, FlixBus, Tornado Bus, Greyhound.
What are the earliest and latest departure times for the bus from Greenville to Durham?
The earliest bus departs from Greenville to Durham at 7:25am. And the latest bus departs at 10:00pm.
What are the CO₂ emissions for the bus trip from Greenville to Durham?
A bus trip from Greenville to Durham generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Greenville to Durham?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11648 reviews.
Which bus company has the best Wi-Fi from Greenville to Durham?
Based on Busbud reviews, the bus company Tornado Bus has the highest Wi-Fi rating with a score of 4.0.
Which bus company has the best on-time performance from Greenville to Durham?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Greenville to Durham?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Durham, NC, US was searched and found on Jan 2, 2026 with a price of $62To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Durham, NC, US, as early as possible.
What's the cheapest way to go from Greenville, SC to Durham, NC, US?
The bus is the cheapest travel choice for this destination
