Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Framingham Intermodal - 2 Franklin St | Downtown Greyhound Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Framingham Intermodal - 2 Franklin St | 537-517 W. Jackson Blvd | No tags | ||||
| Bus | Framingham Intermodal - 2 Franklin St | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 4:44 PM EST.
Compare 2 ways to go from Framingham to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 9 hours 50 minutes, and with fares starting at just $175, it presents an excellent value for a comfortable ride.
Where are the popular stops in Framingham and Chicago?
Stops in Framingham
- A
Framingham Flutie Pass Bus Stop
43 Flutie Pass Commuter Lot (Park and Ride Lot - Routes 9 & 30 - Exit 13 off I-90), Framingham, MA 01701 - B
Shoppers World Bus Stop
1 Worcester Rd, Framingham, MA 01701, USA - C
Route 9 East Park and Ride
1672 Worcester Rd, Framingham, MA 01702, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 87452 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $177
Frequently asked questions about travelling from Framingham to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Framingham to Chicago?
The cheapest bus tickets from Framingham to Chicago start from $175. The average price for this route is around $227. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Framingham to Chicago?
The average bus travel time from Framingham to Chicago is 1d 9h, covering a distance of 1338 km. The quickest bus can get you there in 1d 6h and is operated by Greyhound.
Which bus companies service the Framingham to Chicago route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Framingham to Chicago?
The earliest bus departs from Framingham to Chicago at 11:35am. And the latest bus departs at 2:45pm.
What are the CO₂ emissions for the bus trip from Framingham to Chicago?
A bus trip from Framingham to Chicago generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Framingham to Chicago was searched and found on Dec 26, 2025 with a price of $167To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Framingham to Chicago, as early as possible.
You can expect to pay from $167 to $368 for a bus ticket from Framingham to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $167 which is on 2025-12-31.
What's the cheapest way to go from Framingham to Chicago?
The bus is the cheapest travel choice for this destination
