Bus Tickets from Florence, SC, US to Tampa

TodayJul 30
TomorrowJul 31
FriAug 1
from US$103
SatAug 2
SunAug 3
from US$102
MonAug 4
from US$87
TueAug 5
from US$87
WedAug 6

Cheap buses leaving Friday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 1 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: August 2 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 1 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: August 1 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: August 2 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: August 2 at
    Destination city: Tampa
    Destination location: University of South Florida
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: August 1 at
    Destination city: Tampa
    Destination location: Tampa Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 12:19 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Florence to Tampa

Bus
Average PriceUS$74 - US$222Average Duration17h 55m
18kg CO₂e5 out of 5 stars
FastestMost eco-friendly
Train
Average PriceUS$73 - US$207Average Duration18h 32m
67kg CO₂e1 out of 5 stars
Cheapest
busbud logoBusbud recommends taking the bus from Florence to Tampa

Among the sustainable travel choices, the bus stands out as a good way to reach Tampa. The journey takes about 17 hours 55 minutes, and with fares starting at just US$74, it presents an excellent value for a comfortable ride.

3bus per day
17h 55mAverage Duration
US$74Cheapest ticket
18kgCO₂ emissions

Bus Florence, SC, US to Tampa: Trip Overview

Average Ticket PriceUS$95
Average Bus Trip Duration17h 55m
Number of daily buses3
Earliest bus departure5:30am
Distance739 km
Latest bus departure4:15pm

Florence to Tampa Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Tampa.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Tampa.

Whether it is cheap bus tickets or more luxurious buses going to Tampa from Florence, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Florence, SC, US - Tampa

  1. What is the distance between Florence and Tampa?

    The distance between Florence and Tampa is approximately 747 km (464 miles).

  2. What are the departure and arrival locations for buses traveling from Florence to Tampa?

    Buses departing from Florence Bus Station in Florence will take you to Tampa 13th Avenue Bus Stop (McDonald's) in Tampa.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-28
US$82
07-29
US$125
Today
No data
07-31
No data
08-01
US$96
08-02
No data
08-03
US$95
08-04
US$79
busbud logoThe cheapest trip from Florence, SC, US to Tampa was searched and found on Aug 4, 2025 with a price of US$79

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Tampa, as early as possible.

You can expect to pay from US$79 to US$198 for a bus ticket from Florence, SC, US to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at US$79 which is on 2025-08-04.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Tampa but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Tampa.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Tampa.

Make a music playlist for your bus ride from Florence to Tampa, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Florence, SC, US to Tampa?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence, SC, US by bus?

Bus from Florence, SC, US to Tampa

You can also go to Tampa by train

Train from Florence, SC, US to Tampa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌